Evidence map›Paper›PMID 32372697›Full record

ArticlePharmacogenomics2020

HLA alleles associated with asparaginase hypersensitivity in childhood ALL: a report from the DFCI Consortium.

Vincent Gagné, Pascal St-Onge, Patrick Beaulieu, Caroline Laverdière, Jean-Marie Leclerc, Thai H Tran, Stephen E Sallan, Donna Neuberg, Lewis B Silverman, Daniel Sinnett and 1 more

Open access · greenAbstract read
In one paragraph

Article in Pharmacogenomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Vincent GagnéCharles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, H3T 1C5, Canada.
Pascal St-OngeCharles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, H3T 1C5, Canada.
Patrick BeaulieuCharles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, H3T 1C5, Canada.
Caroline LaverdièreCharles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, H3T 1C5, Canada.
Jean-Marie LeclercCharles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, H3T 1C5, Canada.
Thai H TranCharles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, H3T 1C5, Canada.
Stephen E SallanDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Donna NeubergDepartment of Biostatistics & Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Lewis B SilvermanDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Daniel SinnettCharles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, H3T 1C5, Canada.
Maja KrajinovicCharles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, H3T 1C5, Canada.
Centre Hospitalier Universitaire Sainte-Justine · CAUniversité de Montréal · CABoston Children's Hospital · USDana-Farber Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsparaginaseChildChild, PreschoolCohort StudiesFemaleHLA-DQ alpha-ChainsHLA-DQ beta-ChainsHLA-DRB1 ChainsHumansMalePrecursor Cell Lymphoblastic Leukemia-LymphomaQuebecAsparaginaseHLA-DQ alpha-ChainsHLA-DQ beta-ChainsHLA-DRB1 Chainsacute lymphoblastic leukemiaasparaginaseasparaginase hypersensitivityhuman leukocyte antigenpharmacogeneticsSNP

Identifiers

PMID32372697
PMCPMC7299187
OpenAlexW3021009918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.