ArticleAnaesthesia2020
The effect on consent rates for deceased organ donation in Wales after the introduction of an opt-out system.
Article in Anaesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Education and Ethical Guidance for Organ Donation at the End-of-Life: An Ethical Guidance Statement from the Neurocritical Care Society.Neurocritical care · 2026Review
- Challenges and Support Strategies for Intensive Care Unit Nurses in the Organ Donation Process: A Scoping Review.Journal of advanced nursing · 2026Article
- Undergraduate medical, health science, and technical students' attitudes and knowledge on organ donation and transplantation.BMC medical education · 2025Observational
- Perceptions and experiences of healthcare professionals of implementing the Organ Donation (Deemed Consent) Act in England during the Covid-19 pandemic.BMC health services research · 2025Article
- Assessment of the relationship between organ donation attitudes and religious beliefs among postgraduate students.Frontiers in public health · 2025Article
- Protocol and Statistical Analysis Plan for a Comparative Interrupted Time Series Evaluation of the Impact of Deemed Consent for Organ Donation Legislative Reform in Nova Scotia, Canada.Transplantation direct · 2024Article
- "I am in favour of organ donation, but I feel you should opt-in"-qualitative analysis of the #options 2020 survey free-text responses from NHS staff toward opt-out organ donation legislation in England.BMC medical ethics · 2024Article
- Early experiences of deemed consent legislation for organ donation in Nova Scotia: a qualitative study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Article
- Trends in organ donation in England, Scotland and Wales in the context of the COVID-19 pandemic and 'opt-out' legislation.PloS one · 2024Article
- Post-COVID-19 pandemic organ donation activities in Germany: a multicenter retrospective analysis.Frontiers in public health · 2024Article
- Organ Donation Awareness among Family Members of ICU Patients.Medicina (Kaunas, Lithuania) · 2023Article
- How clinicians discuss patients' donor registrations of consent and presumed consent in donor conversations in an opt-out system: a qualitative embedded multiple-case study.Critical care (London, England) · 2023Article
- Messaging strategies for communicating health-related information in social media-a content and effectiveness analysis of organ donation posts on Instagram in Germany.BMC public health · 2023Article
- Organ and Tissue Donation Consent Model and Intent to Donate Registries: Recommendations From an International Consensus Forum.Transplantation direct · 2023Article
- Kidney xenotransplantation: Future clinical reality or science fiction?Nursing & health sciences · 2023Article
- Solid Organ Donation and Transplantation in the United Kingdom: Good Governance is Key to Success.Transplant international : official journal of the European Society for Organ Transplantation · 2023Review
- How Large is the Potential of Brain Dead Donors and what Prevents Utilization? A Multicenter Retrospective Analysis at Seven University Hospitals in North Rhine-Westphalia.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- A Conceptual Framework for Evaluating National Organ Donation and Transplantation Programs.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Differential impact of opt-in, opt-out policies on deceased organ donation rates: a mixed conceptual and empirical study.BMJ open · 2022Article
- Cost-Effectiveness and Budget Impact Analysis of Implementing a 'Soft Opt-Out' System for Kidney Donation in Australia.Applied health economics and health policy · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organ transplantation saves and transforms lives. Failure to secure consent for organ retrieval is widely regarded as the single most important obstacle to transplantation. A soft opt-out system of consent for deceased organ donation was introduced into Wales in December 2015, whilst England maintained the existing opt-in system. Cumulative data on consent rates in Wales were compared with those in England, using a two-sided sequential procedure that was powered to detect an absolute difference in consent rates between England and Wales of 10%. Supplementary risk-adjusted logistic regression analysis examined whether any difference in consent rates between the two nations could be attributed to variations in factors known to influence UK consent rates. Between 1 January 2016 and 31 December 2018, 8192 families of eligible donors in England and 474 in Wales were approached regarding organ donation, with overall consent rates of 65% and 68%, respectively. There was a steady upward trend in the proportion of families consenting to donation after brain death in Wales as compared with England and after 33 months, this reached statistical significance. No evidence of any change in the donation after circulatory death consent rate was observed. Risk-adjusted logistic regression analysis revealed that by the end of the study period the probability of consent to organ donation in Wales was higher than in England (OR [95%CI] 2.1 [1.26-3.41]). The introduction of a soft opt-out system of consent in Wales significantly increased organ donation consent though the impact was not immediate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.