Evidence map›Paper›PMID 32372322›Full record

ArticleEating and weight disorders : EWD2021

The song of Anorexia Nervosa: a specific evoked potential response to musical stimuli in affected participants.

Angela Valentina Spalatro, Marco Marzolla, Sergio Vighetti, Giovanni Abbate Daga, Secondo Fassino, Benedetto Vitiello, Federico Amianto

Open access · greenAbstract read

PubMed Publisher

In one paragraph

Article in Eating and weight disorders : EWD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

0.5field-weighted citation impact, top 41% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

Cariprazine as a candidate for drug repurposing in anorexia nervosa: a mechanistic hypothesis grounded in neuroimaging evidence.Frontiers in pharmacology · 2026
Article
Using Electroencephalogram-Extracted Nonlinear Complexity and Wavelet-Extracted Power Rhythm Features during the Performance of Demanding Cognitive Tasks (Aristotle's Syllogisms) in Optimally Classifying Patients with Anorexia Nervosa.Brain sciences · 2024
Article
Tuning in to recovery: influence of music on emotional well-being during mealtime in inpatient facilities for eating disorders.Journal of eating disorders · 2024
Article

4 · The record

Corrections and comments

Commented on by
Answer to the Letter about "The song of Anorexia Nervosa: a specific evoked potential response to musical stimuli in affected participants" by Spalatro et al. (https://doi.org/10.1007/s40519-020-00898-4), published online: 05 May 2020.2021

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Angela Valentina SpalatroSection of Psychiatry, Department of Neuroscience, Eating Disorders Centre, University of Turin, Via Cherasco 11, 10135, Turin, Italy.

Marco MarzollaSection of Psychiatry, Department of Neuroscience, Eating Disorders Centre, University of Turin, Via Cherasco 11, 10135, Turin, Italy.

Sergio VighettiSection of Neurophysiology, Department of Neuroscience, University of Turin, Via Cherasco 15, 10135, Turin, Italy.

Giovanni Abbate DagaSection of Psychiatry, Department of Neuroscience, Eating Disorders Centre, University of Turin, Via Cherasco 11, 10135, Turin, Italy.

Secondo FassinoSection of Psychiatry, Department of Neuroscience, Eating Disorders Centre, University of Turin, Via Cherasco 11, 10135, Turin, Italy.

Benedetto VitielloDepartment of Public Health and Pediatric Sciences, Child and Adolescent Neuropsychiatry, University of Turin, P.zza Polonia 94, Via Cherasco 11, 10126, Turin, Italy.

Federico AmiantoSection of Psychiatry, Department of Neuroscience, Eating Disorders Centre, University of Turin, Via Cherasco 11, 10135, Turin, Italy. federico.amianto@unito.it.

University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeResearch applying electroencephalography (EEG) to Anorexia Nervosa (AN) is still limited, even though in other psychiatric disorders EEG has permitted to find out the hallmarks of the disorder. The aim of the study was to explore whether EEG basal activity and reactivity to musical stimulation differ in participants with AN as compared to healthy subjects (HS).

methodsTwenty female participants (respectively 10 with AN and 10 healthy controls) were administered a battery of psychometric tests and underwent EEG under three different conditions: (1) at baseline; (2) after a generic music stimulation; and (3) after a favorite musical stimulation.

resultsIn participants with AN, basal EEG showed the higher absolute amplitude of cortical slow waves (theta) in the parieto-occipital and temporal derivations, with a deficit in the beta band. In AN, there was a higher N100 latency and a reduced P300 latency compared to HS. While the N100 and P300 latencies were sensitive to the musical stimulus in HS, there was no difference after music stimulation in AN.

conclusionThese data suggest that AN is accompanied by a state of brain hyperarousal with abnormal reactivity to environmental stimuli, similar to the state of HS after musical stimulation. If confirmed, this finding may have treatment implications. LEVEL OF EVIDENCE: III, Evidence obtained from well-designed cohort or case-control analytic studies.

Indexed as

Anorexia NervosaMusicAuditory PerceptionElectroencephalographyEvoked PotentialsFemaleHumansAnorexia nervosaEEG activityHyperarousalMusic therapyp300Slow waves

Identifiers

PMID32372322

DOI10.1007/s40519-020-00898-4

OpenAlexW3023339355

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.