Evidence map›Paper›PMID 32372165›Full record

ArticleInflammopharmacology2020

Tannic acid alleviates experimental pulmonary fibrosis in mice by inhibiting inflammatory response and fibrotic process.

Nandhine Rajasekar, Ayyanar Sivanantham, Amrita Kar, Santanu Kar Mahapatra, Rajesh Ahirwar, Rajesh K Thimmulappa, Sudhakar Gandhi Paramasivam, Rajasekaran Subbiah

Abstract read
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In one paragraph

Article in Inflammopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nandhine RajasekarDepartment of Biotechnology, BIT-Campus, Anna University, Tiruchirappalli, Tamil Nadu, 620024, India.
Ayyanar SivananthamDepartment of Biotechnology, BIT-Campus, Anna University, Tiruchirappalli, Tamil Nadu, 620024, India.
Amrita KarCentre for Research in Infectious Diseases (CRID), School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, 613401, India.
Santanu Kar MahapatraCentre for Research in Infectious Diseases (CRID), School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, 613401, India.
Rajesh AhirwarDepartment of Biochemistry, ICMR-National Institute for Research in Environmental Health, Bhopal, Madhya Pradesh, 462030, India.
Rajesh K ThimmulappaDepartment of Biochemistry, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, Karnataka, 570015, India.
Sudhakar Gandhi ParamasivamDepartment of Biotechnology, BIT-Campus, Anna University, Tiruchirappalli, Tamil Nadu, 620024, India. gandhisivam@gmail.com.ORCID http://orcid.org/0000-0002-7715-9074
Rajasekaran SubbiahDepartment of Biotechnology, BIT-Campus, Anna University, Tiruchirappalli, Tamil Nadu, 620024, India. rajasekaran.s@icmr.gov.in.ORCID http://orcid.org/0000-0003-2303-3246
Anna University, Chennai · INSASTRA University · INICMR National Institute for Research in Environmental HealthJSS Academy of Higher Education and Research · IN

Funding

Department of Biotechnology , Ministry of Science and Technology BT/RLF/Re-entry/36/2013Science and Engineering Research Board YSS/2014/000125
6 · The paper itself

Abstract

Pulmonary fibrosis (PF) is a chronic and irreversible scarring disease in the lung with limited treatment options. Therefore, it is critical to identify new therapeutic options. This study was undertaken to identify the effects of tannic acid (TA), a naturally occurring dietary polyphenol, in a mouse model of PF. Bleomycin (BLM) was intratracheally administered to induce PF. Administration of TA significantly reduced BLM-induced histological alterations, inflammatory cell infiltration and the levels of various inflammatory mediators (nitric oxide, leukotriene B

Indexed as

AnimalsAnti-Inflammatory AgentsBleomycinDisease Models, AnimalInflammationInflammation MediatorsMiceMice, Inbred C57BLPulmonary FibrosisTanninsAnti-Inflammatory AgentsBleomycinInflammation MediatorsTanninsBleomycinInflammationNatural compoundPulmonary fibrosisTannic acidTransforming growth factor-β

Identifiers

PMID32372165
OpenAlexW3021417024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.