ArticleNature communications2020
Magnetically driven active topography for long-term biofilm control.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 85 citations in OpenAlex.
- Antibacterial surface engineering: bioinspiration from leaves to medical devices.RSC applied interfaces · 2026Review
- Nature-inspired biomaterial innovations to counter medical device-associated infections.Biomaterials science · 2026Review
- Laser-Guided Self-Rolled Magnetic Microrobots for Targeted Biofilm Eradication in Severely Infected Medical Stents.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Dynamically actuated reconfigurable topographical surface enables active control of implant-associated infections.bioRxiv : the preprint server for biology · 2026Article
- Design of a Chitinase-Responsive, Depolymerizable Petroleum-Derived Polymer for Circular and Antifouling Materials.ACS applied polymer materials · 2026Article
- On-demand biofilm removal by shape-memory triggered local changes in surface topography.MRS bulletin · 2026Article
- A rational approach to discovering new persister control agents.Antimicrobial agents and chemotherapy · 2025Article
- Engineering multifunctional surface topography to regulate multiple biological responses.Biomaterials · 2025Review
- Ultrasound-activated cilia for biofilm control in indwelling medical devices.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Review
- Role ofMicroorganisms · 2024Article
- Targeting biofilm infections in humans using small scale robotics.Trends in biotechnology · 2024Review
- Dissolvable alginate hydrogel-based biofilm microreactors for antibiotic susceptibility assays.Biofilm · 2023Article
- Strategies and materials for the prevention and treatment of biofilms.Materials today. Bio · 2023Review
- Effects of Synthetic Tetronamides and Methylated Denigrins on Bacterial Quorum Sensing and Biofilm Formation.ACS omega · 2023Article
- Biofilms: Formation, Research Models, Potential Targets, and Methods for Prevention and Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Gallium-Based Liquid Metal Materials for Antimicrobial Applications.Bioengineering (Basel, Switzerland) · 2022Review
- High-Throughput Biofilm Assay to Investigate Bacterial Interactions with Surface Topographies.ACS applied bio materials · 2022Article
- Recent Progress on Bioinspired Antibacterial Surfaces for Biomedical Application.Biomimetics (Basel, Switzerland) · 2022Review
- Magneto-Mechanical Enhancement of Elastic Moduli in Magnetoactive Elastomers with Anisotropic Microstructures.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Microbial biofilm formation on indwelling medical devices causes persistent infections that cannot be cured with conventional antibiotics. To address this unmet challenge, we engineer tunable active surface topographies with micron-sized pillars that can beat at a programmable frequency and force level in an electromagnetic field. Compared to the flat and static controls, active topographies with the optimized design prevent biofilm formation and remove established biofilms of uropathogenic Escherichia coli (UPEC), Pseudomonas aeruginosa, and Staphylococcus aureus, with up to 3.7 logs of biomass reduction. In addition, the detached biofilm cells are found sensitized to bactericidal antibiotics to the level comparable to exponential-phase planktonic cells. Based on these findings, a prototype catheter is engineered and found to remain clean for at least 30 days under the flow of artificial urine medium, while the control catheters are blocked by UPEC biofilms within 5 days.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.