ArticleJournal of hypertension2020
The association of outdoor temperature with blood pressure, and its influence on future cardio-cerebrovascular disease risk in cold areas.
Article in Journal of hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Pooled incidence and case-fatality of acute stroke in Mainland China, Hong Kong, and Macao: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Seasonal variation in the office and ambulatory blood pressure control in patients treated with two dual antihypertensive therapies.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Effect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Food science & nutrition · 2026Review
- The individual and joint effects of long-term exposure to temperature and relative humidity on blood pressure: a prospective cohort study in China.BMC public health · 2025Article
- Multiple Environmental Exposures and the Development of Hypertension in a Prospective US-Based Cohort of Female Nurses: A Mixture Analysis.Environmental science & technology · 2024Article
- Article
- Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults.Nature communications · 2024Article
- Association of ambient temperature on acute ischemic stroke in Yancheng, China.BMC public health · 2024Article
- Heat exposure induced risks of preterm birth mediated by maternal hypertension.Nature medicine · 2024Article
- Effects of PMFrontiers in public health · 2024Article
- The Modern Environment: The New Secondary Cause of Hypertension?Medicina (Kaunas, Lithuania) · 2023Review
- Adapting an In-Home Randomized Intervention Trial Protocol for COVID-19 Precautions.International journal of environmental research and public health · 2023Article
- Temperature variability increases the onset risk of ischemic stroke: A 10-year study in Tianjin, China.Frontiers in neurology · 2023Article
- Review
- Bayes Conditional Probability-Based Causation Analysis between Gestational Diabetes Mellitus (GDM) and Pregnancy-Induced Hypertension (PIH): A Statistic Case Study in Harbin, China.Journal of diabetes research · 2022Article
- The relationship between home blood pressure measurement and room temperature in a Japanese general population.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Daily Meteorological Parameters Influence the Risk of Intracerebral Hemorrhage in a Subtropical Monsoon Basin Climate.Risk management and healthcare policy · 2021Article
- Optimal Antihypertensive Medication Adherence Reduces the Effect of Ambient Temperature on Intracerebral Hemorrhage Occurrence: A Case-Crossover Study.Patient preference and adherence · 2021Article
- Effect and Relationship of Seasons on the High Risk of Ovarian Hyperstimulation Syndrome After Oocyte Retrieval in Patients With Polycystic Ovary Syndrome.Frontiers in endocrinology · 2020Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 2 countries.
Funding
Abstract
objectivesTo explore whether lower outdoor temperature increases cardio-cerebrovascular disease risk through regulating blood pressure and whether indoor heating in winter is beneficial to prevent cardio-cerebrovascular disease in cold areas.
methodsWe analyzed the data of 38 589 participants in Harbin from the China Kadoorie Biobank (CKB) during 2004-2008, with an average of 7.14-year follow-up. Linear regression analysis was performed to estimate the relationship between outdoor temperature and blood pressure. Cox regression analysis and logistic regression analysis were used to analyze the association of blood pressure with cardio-cerebrovascular event risk. Mediation analysis was performed to explore the role of blood pressure in the association between outdoor temperature and cardio-cerebrovascular events risk.
resultsThere was an increase of 6.7 mmHg in SBP and 2.1 mmHg in DBP for each 10 °C decrease in outdoor temperature when outdoor temperature was higher than 5 °C. There was an inverse association between outdoor temperature and cardio-cerebrovascular event morbidity. The increases in blood pressure and cardio-cerebrovascular event morbidity were attenuated in months when central heating was fully provided. Participants with hypertension have higher risks of cardio-cerebrovascular disease (hazard ratio 1.347; 95% CI 1.281--1.415), CVD (hazard ratio 1.347; 95% CI 1.282--1.416), MACE (hazard ratio 1.670; 95% CI 1.560--1.788) and stroke (hazard ratio 1.683; 95% CI 1.571--1.803). Mediation analysis demonstrated that the association between outdoor temperature and cardio-cerebrovascular events risk was potentially mediated by blood pressure.
conclusionTemperature-driven blood pressure potentially mediates the association between outdoor temperature and cardio-cerebrovascular events risk. Indoor heating in winter is probably beneficial to cardio-cerebrovascular disease prevention by inhibition of blood pressure increase.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.