Evidence map›Paper›PMID 32371771›Full record

ArticleJournal of hypertension2020

Associations between carotid-femoral and heart-femoral pulse wave velocity in older adults: the Atherosclerosis Risk In Communities study.

Lee Stoner, Michelle L Meyer, Anna Kucharska-Newton, Keeron Stone, Gabriel Zieff, Gaurav Dave, Simon Fryer, Daniel Credeur, James Faulkner, Kunihiro Matsushita and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Lee StonerDepartment of Exercise and Sport Science.
Michelle L MeyerDepartment of Emergency Medicine, School of Medicine.
Anna Kucharska-NewtonDepartment of Epidemiology, The Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Keeron StoneSchool of Sport and Exercise, University of Gloucestershire, Gloucester, UK.
Gabriel ZieffDepartment of Exercise and Sport Science.
Gaurav DaveDivision of General Internal Medicine and Clinical Epidemiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Simon FryerSchool of Sport and Exercise, University of Gloucestershire, Gloucester, UK.
Daniel CredeurSchool of Kinesiology, University of Southern Mississippi, Hattiesburg, Mississippi, USA.
James FaulknerDepartment of Sport & Exercise, University of Winchester, Winchester, UK.
Kunihiro MatsushitaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Timothy M HughesSection of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina.
Hirofumi TanakaDepartment of Kinesiology and Health Education, The University of Texas at Austin, Austin, Texas, USA.
University of Gloucestershire · GBUniversity of North Carolina at Chapel Hill · USJohns Hopkins University · USThe University of Texas at Austin · USUniversity of Kentucky · USUniversity of Southern Mississippi · USUniversity of Winchester · GBWake Forest University · US

Funding

Changes in arterial stiffness, cognition and dementia risk in a diverse cohortR01AG053938 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MEYER, MICHELLE · 2016 to 2020
$2.9M
NHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INIA NIH HHS R01 AG053938
6 · The paper itself

Abstract

backgroundCarotid-femoral pulse wave velocity (cfPWV) is widely used in epidemiological studies to assess central arterial stiffness. However, despite being superior to traditional risk factors in predicting cardiovascular outcomes, cfPWV is not routinely used in clinical practice. cfPWV assessments require applanation of the carotid artery, which can be cumbersome, and individual-level factors, including carotid artery plaque, may confound the measurements. Heart-femoral PWV (hfPWV) may be a suitable alternative measure of central arterial stiffness.

objectivesThe aim of this study was to estimate the strength of the agreement between hfPWV and cfPWV.

methodsWe evaluated 4133 older-aged [75.2 (5.0) years] African-American and white adults in the community-based Atherosclerosis Risk in Communities (ARIC) Study. cfPWV and hfPWV were measured using an automated cardiovascular screening device. Agreement between the two measurements was determined using Pearson's correlation coefficient (r), standard error of estimate (SEE) and Bland-Altman analysis.

resultsThere was a strong (r > 0.7) agreement between hfPWV and cfPWV (r = 0.83, 95% CI: 0.82-0.84). Although the mean cfPWV [11.5 m/s (SD: 3.0)] and hfPWV [11.5 m/s (SD: 2.3)] were comparable, the SEE was 1.7 m/s. Inspection of the Bland-Altman plot revealed greater variability and bias for higher PWV values, with higher PWV further away from the regression line. DISCUSSION: Findings suggest good agreement between hfPWV and cfPWV. hfPWV is a simpler alternative to cfPWV that is less likely to be confounded by individual-level factors. Considering the greater variability for higher PWV values, further work is warranted to determine the importance of local artery mechanics to both measures.

Indexed as

AtherosclerosisAgedAged, 80 and overCarotid ArteriesFemoral ArteryHumansPulse Wave AnalysisRisk Factors

Identifiers

PMID32371771
PMCPMC7415670
OpenAlexW3013291400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.