ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020
The Degree of Nesting between Spindles and Slow Oscillations Modulates Neural Synchrony.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Exposure to broadband noise during non-REM sleep impairs hippocampal sharp-wave ripples and memory consolidation.Current biology : CB · 2026Article
- Spatially Extensive LFP Correlations Identify Slow-Wave Sleep in Marmoset Sensorimotor Cortex.eNeuro · 2025Article
- Coupling of Slow Oscillations in the Prefrontal and Motor Cortex Predicts Onset of Spindle Trains and Persistent Memory Reactivations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Sleep Consolidation Potentiates Sensorimotor Adaptation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Spindle oscillations in communicating axons within a reconstituted hippocampal formation are strongest in CA3 without thalamus.Scientific reports · 2024Article
- Disturbed laterality of non-rapid eye movement sleep oscillations in post-stroke human sleep: a pilot study.medRxiv : the preprint server for health sciences · 2023Article
- Sleep Spindles Favor Emotion Regulation Over Memory Consolidation of Stressors in Posttraumatic Stress Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- How coupled slow oscillations, spindles and ripples coordinate neuronal processing and communication during human sleep.Nature neuroscience · 2023Article
- Highly synchronized cortical circuit dynamics mediate spontaneous pain in mice.The Journal of clinical investigation · 2023Article
- Adaptive control of synaptic plasticity integrates micro- and macroscopic network function.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Review
- Disturbed laterality of non-rapid eye movement sleep oscillations in post-stroke human sleep: a pilot study.Frontiers in neurology · 2023Article
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- Recovery of consolidation after sleep following stroke-interaction of slow waves, spindles, and GABA.Cell reports · 2022Article
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- Cortico-Hippocampal Oscillations Are Associated With the Developmental Onset of Hippocampal-Dependent Memory.Frontiers in neuroscience · 2022Article
- Coupling between motor cortex and striatum increases during sleep over long-term skill learning.eLife · 2021Article
- Twitches emerge postnatally during quiet sleep in human infants and are synchronized with sleep spindles.Current biology : CB · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Spindles and slow oscillations (SOs) both appear to play an important role in memory consolidation. Spindle and SO "nesting," or the temporal overlap between the two events, is believed to modulate consolidation. However, the neurophysiological processes modified by nesting remain poorly understood. We thus recorded activity from the primary motor cortex of 4 male sleeping rats to investigate how SO and spindles interact to modulate the correlation structure of neural firing. During spindles, primary motor cortex neurons fired at a preferred phase, with neural pairs demonstrating greater neural synchrony, or correlated firing, during spindle peaks. We found a direct relationship between the temporal proximity between SO and spindles, and changes to the distribution of neural correlations; nesting was associated with narrowing of the distribution, with a reduction in low- and high-correlation pairs. Such narrowing may be consistent with greater exploration of neural states. Interestingly, after animals practiced a novel motor task, pairwise correlations increased during nested spindles, consistent with targeted strengthening of functional interactions. These findings may be key mechanisms through which spindle nesting supports memory consolidation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.