Evidence map›Paper›PMID 32371598›Full record

ArticlemBio2020

Loss of Bacterial Cell Pole Stabilization in Caulobacter crescentus Sensitizes to Outer Membrane Stress and Peptidoglycan-Directed Antibiotics.

Simon-Ulysse Vallet, Lykke Haastrup Hansen, Freja Cecillie Bistrup, Signe Aagaard Laursen, Julien Bortoli Chapalay, Marc Chambon, Gerardo Turcatti, Patrick H Viollier, Clare L Kirkpatrick

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Envelope destabilization by AcrABCommunications biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. TipN's involvement with centromere segregation in Caulobacter crescentus.bioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Simon-Ulysse ValletDepartment of Microbiology and Molecular Medicine, Institute of Genetics and Genomics in Geneva (iG3), Faculty of Medicine/CMU, University of Geneva, Geneva, Switzerland.
Lykke Haastrup HansenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Freja Cecillie BistrupDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Signe Aagaard LaursenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Julien Bortoli ChapalayBiomolecular Screening Facility, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Marc ChambonBiomolecular Screening Facility, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Gerardo TurcattiBiomolecular Screening Facility, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Patrick H ViollierDepartment of Microbiology and Molecular Medicine, Institute of Genetics and Genomics in Geneva (iG3), Faculty of Medicine/CMU, University of Geneva, Geneva, Switzerland.
Clare L KirkpatrickDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark clarek@bmb.sdu.dk.ORCID 0000-0001-8564-8559
University of Southern Denmark · DKÉcole Polytechnique Fédérale de Lausanne · CHUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rod-shaped bacteria frequently localize proteins to one or both cell poles in order to regulate processes such as chromosome replication or polar organelle development. However, the roles of polar factors in responses to extracellular stimuli have been generally unexplored. We employed chemical-genetic screening to probe the interaction between one such factor from

Indexed as

Anti-Bacterial AgentsBacterial Outer MembraneBacterial ProteinsCaulobacter crescentusDrug Resistance, BacterialPeptidoglycanStress, PhysiologicalAnti-Bacterial AgentsBacterial ProteinsPeptidoglycanantibiotic resistanceCaulobacter crescentuscell envelopecell polarityTonB-dependent receptorvancomycin

Identifiers

PMID32371598
PMCPMC7403779
OpenAlexW3023276116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.