Evidence map›Paper›PMID 32371597›Full record

ArticlemBio2020

Linearized Siderophore Products Secreted via MacAB Efflux Pump Protect Salmonella enterica Serovar Typhimurium from Oxidative Stress.

L M Bogomolnaya, R Tilvawala, J R Elfenbein, J D Cirillo, H L Andrews-Polymenis

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Role of bacterial multidrug efflux pumps during infection.World journal of microbiology & biotechnology · 2024
    Review
  5. Article
  6. Non-classical roles of bacterial siderophores in pathogenesis.Frontiers in cellular and infection microbiology · 2024
    Review
  7. Article
  8. Implication of the σMicrobiology spectrum · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Manganese Utilization inFrontiers in cell and developmental biology · 2022
    Review
  14. Article
  15. Article
  16. Recent Advances in the Siderophore Biology ofFrontiers in microbiology · 2022
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

L M BogomolnayaTexas A&M University Health Science Center, Bryan, Texas, USA.
R TilvawalaTexas A&M University Health Science Center, Bryan, Texas, USA.
J R ElfenbeinNorth Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.
J D CirilloTexas A&M University Health Science Center, Bryan, Texas, USA.
H L Andrews-PolymenisTexas A&M University Health Science Center, Bryan, Texas, USA handrews@tamu.edu.
Texas A&M Health Science Center · USKazan Federal University · RUNorth Carolina State University · US

Funding

Functional dissection of the retron St-85 of Salmonella TyphimuriumK08AI108794 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ELFENBEIN, JOHANNA REBECCA · 2014 to 2017
$602k
Defining the molecular mechanisms of MacAB in protection of Salmonella from oxidative stressR21AI123965 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ANDREWS-POLYMENIS, HELENE L · 2016 to 2017
$408k
NIAID NIH HHS K08 AI108794NIAID NIH HHS R21 AI123965
6 · The paper itself

Abstract

Nontyphoidal salmonellae (NTS) are exposed to reactive oxygen species (ROS) during their residency in the gut. To survive oxidative stress encountered during infection, salmonellae employ several mechanisms. One of these mechanisms involves the multidrug efflux pump MacAB, although the natural substrate of this pump has not been identified. MacAB homologs in pseudomonads secrete products of nonribosomal peptide synthesis (NRPS). In

Indexed as

Oxidative StressAnimalsATP-Binding Cassette TransportersBacterial ProteinsBiological TransportCattleEnterobactinFemaleHydrogen PeroxideIronMiceMice, Inbred C57BLPeptide Biosynthesis, Nucleic Acid-IndependentPeptide SynthasesReactive Oxygen SpeciesSalmonella typhimuriumATP-Binding Cassette TransportersBacterial ProteinsEnterobactinHydrogen PeroxideIronPeptide SynthasesReactive Oxygen SpeciessalmochelinSiderophoresMacABmultidrug efflux pumpSalmonellasiderophores

Identifiers

PMID32371597
PMCPMC7403778
OpenAlexW3023054720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.