Evidence map›Paper›PMID 32371595›Full record

ArticlemBio2020

Systemic Inflammatory Mediators Are Effective Biomarkers for Predicting Adverse Outcomes in Clostridioides difficile Infection.

Michael G Dieterle, Rosemary Putler, D Alexander Perry, Anitha Menon, Lisa Abernathy-Close, Naomi S Perlman, Aline Penkevich, Alex Standke, Micah Keidan, Kimberly C Vendrov and 3 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Metabolic Syndrome Is Associated With Increased Risk ofOpen forum infectious diseases · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Antibiotics (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Gut community alterations associated withFrontiers in microbiology · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Journal of inflammation research · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Michael G DieterleMedical Scientist Training Program, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0002-3109-6151
Rosemary PutlerInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
D Alexander PerryInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Anitha MenonInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Lisa Abernathy-CloseDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-6543-7014
Naomi S PerlmanInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Aline PenkevichInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Alex StandkeInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Micah KeidanInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Kimberly C VendrovInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Ingrid L BerginUnit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Vincent B YoungDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-3687-2364
Krishna RaoInfectious Diseases Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA krirao@med.umich.edu.ORCID 0000-0002-9213-7850
University of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Systems biology of Clostridium difficile infectionU01AI124255 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID, YOUNG, VINCENT B · 2016 to 2020
$9.8M
Training in Basic and Translational Digestive SciencesT32DK094775 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHN Y KAO, LINDA C. SAMUELSON · 2012 to 2026
$3.6M
Host and Microbial Biomarkers Related to the Development of Complicated Clostridium difficile InfectionR21AI120599 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YOUNG, VINCENT B · 2015 to 2016
$426k
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NIAID NIH HHS R21 AI120599NIAID NIH HHS U01 AI124255NIA NIH HHS P30 AG024824NIDDK NIH HHS T32 DK094775NIGMS NIH HHS T32 GM007863
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAnimalsBiomarkersClostridioides difficileClostridium InfectionsDisease Models, AnimalFemaleHumansInflammation MediatorsMaleMiceMiddle AgedPilot ProjectsPredictive Value of TestsPrognosisBiomarkersInflammation MediatorsbiomarkersClostridioides difficileClostridium difficilecytokinesmachine learningpredictive modeling

Identifiers

PMID32371595
PMCPMC7403776
OpenAlexW3021895559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.