Evidence map›Paper›PMID 32371439›Full record

ArticleGenetics2020

Fear and Foxes: An Educational Primer for Use with "Anterior Pituitary Transcriptome Suggests Differences in ACTH Release in Tame and Aggressive Foxes".

Julie H Simpson

Open access · hybridAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Julie H SimpsonDepartment of Molecular, Cellular and Developmental Biology and Neuroscience Research Institute, University of California, Santa Barbara, California 93106-9625 jhsimpson@ucsb.edu.ORCID 0000-0002-6793-7100
University of California, Santa Barbara · US

Funding

Sensory control of a motor sequenceR01NS110866 · NINDS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI SIMPSON, JULIE H · 2019 to 2023
$1.9M
Dopaminergic modulation of the fly grooming sequenceR21NS114618 · NINDS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI SIMPSON, JULIE H · 2020 to 2020
$427k
NINDS NIH HHS R01 NS110866NINDS NIH HHS R21 NS114618
6 · The paper itself

Abstract

The way genes contribute to behavior is complicated. Although there are some single genes with large contributions, most behavioral differences are due to small effects from many interacting genes. This makes it hard to identify the genes that cause behavioral differences. Mutagenesis screens in model organisms, selective breeding experiments in animals, comparisons between related populations with different behaviors, and genome-wide association studies in humans are promising and complementary approaches to understanding the heritable aspects of complex behaviors. To connect genes to behaviors requires measuring behavioral differences, locating correlated genetic changes, determining when, where, and how these candidate genes act, and designing causative confirmatory experiments. This area of research has implications from basic discovery science to human mental health.

Indexed as

Behavior, AnimalTranscriptomeAdrenocorticotropic HormoneAggressionAnimalsFearFoxesGenetics, BehavioralMolecular BiologyPituitary GlandAdrenocorticotropic HormoneBehavioral geneticseducationgene expressiontameness

Identifiers

PMID32371439
PMCPMC7198266
OpenAlexW3022926014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.