Evidence map›Paper›PMID 32371438›Full record

ReviewGenetics2020

Phenotypic Plasticity: From Theory and Genetics to Current and Future Challenges.

Ralf J Sommer

Abstract readReview
In one paragraph

Review in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers.

0numbers the graph read from it
0cells of the map it votes in
151citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

151 citing papers in PubMed.

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  12. Oligometastatic Prostate Cancer: Clues from an N-of-1.Journal of clinical medicine · 2026
    Article
  13. AScience signaling · 2026
    Article
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  18. Review
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91 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ralf J SommerMax Planck Institute for Developmental Biology, Department for Integrative Evolutionary Biology, 72076 Tübingen, Germany ralf.sommer@tuebingen.mpg.de.ORCID 0000-0003-1503-7749

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenotypic plasticity is defined as the property of organisms to produce distinct phenotypes in response to environmental variation. While for more than a century, biologists have proposed this organismal feature to play an important role in evolution and the origin of novelty, the idea has remained contentious. Plasticity is found in all domains of life, but only recently has there been an increase in empirical studies. This contribution is intended as a fresh view and will discuss current and future challenges of plasticity research, and the need to identify associated molecular mechanisms. After a brief summary of conceptual, theoretical, and historical aspects, some of which were responsible for confusion and contention, I will formulate three major research directions and predictions for the role of plasticity as a facilitator of novelty. These predictions result in a four-step model that, when properly filled with molecular mechanisms, will reveal plasticity as a major factor of evolution. Such mechanistic insight must be complemented with comparative investigations to show that plasticity has indeed created novelty and innovation. Together, such studies will help develop a true developmental

Indexed as

Adaptation, PhysiologicalAnimalsEvolution, MolecularGene-Environment InteractionHumanscanalizationgenetic accommodationgenetic assimilationManducaOntophagusphenotypic plasticityplasticity first evolutionpolyphenismsPristionchusSpeaswitch genes

Identifiers

PMID32371438
PMCPMC7198268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.