Evidence map›Paper›PMID 32371396›Full record

ArticleThe Journal of biological chemistry2020

The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors.

Filip Trcka, Michal Durech, Pavla Vankova, Veronika Vandova, Oliver Simoncik, Daniel Kavan, Borivoj Vojtesek, Petr Muller, Petr Man

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. From the cytosol to the inner membrane: biogenesis of the mitochondrial carrier family.Protein science : a publication of the Protein Society · 2026
    Review
  2. Mitochondrial presequences are more than just address labels.Protein science : a publication of the Protein Society · 2026
    Review
  3. Article
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  10. Probing Antibody Structures by Hydrogen/Deuterium Exchange Mass Spectrometry.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  11. Article
  12. Review
  13. 14-3-3σ and Its Modulators in Cancer.Pharmaceuticals (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Filip TrckaRegional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Michal DurechRegional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Pavla VankovaBioCeV, Institute of Microbiology of the Czech Academy of Sciences, Vestec, Czech Republic; Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic.
Veronika VandovaRegional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Oliver SimoncikRegional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Daniel KavanBioCeV, Institute of Microbiology of the Czech Academy of Sciences, Vestec, Czech Republic; Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic.
Borivoj VojtesekRegional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Petr MullerRegional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic. Electronic address: muller@mou.cz.
Petr ManBioCeV, Institute of Microbiology of the Czech Academy of Sciences, Vestec, Czech Republic. Electronic address: pman@biomed.cas.cz.
Masaryk Memorial Cancer Institute · CZCzech Academy of Sciences · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Translocase of outer mitochondrial membrane 34 (TOMM34) orchestrates heat shock protein 70 (HSP70)/HSP90-mediated transport of mitochondrial precursor proteins. Here, using

Indexed as

14-3-3 ProteinsCyclic AMP-Dependent Protein KinasesDNA-Binding ProteinsHSP70 Heat-Shock ProteinsHSP72 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsHumansMCF-7 CellsMitochondrial MembranesMitochondrial Membrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsMitochondrial ProteinsMolecular ChaperonesPhosphorylationProtein BindingSignal Transduction14-3-3 ProteinsBCL2-associated athanogene 1 proteinCyclic AMP-Dependent Protein KinasesDNA-Binding ProteinsHSP70 Heat-Shock ProteinsHSP72 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsMitochondrial Membrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsMitochondrial ProteinsMolecular ChaperonesTOMM34 protein, humanTranscription Factors14-3-3 protein70-kDa heat shock protein (Hsp70)dimerizationHsp70HSP70hydrogen-deuterium exchangemolecular chaperonephosphorylationprotein foldingprotein importprotein kinase A (PKA)protein-nucleic acid interactionprotein–protein interactionTomm34translocase of outer mitochondrial membrane 34 (TOMM34)

Identifiers

PMID32371396
PMCPMC7335785
OpenAlexW3022505151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.