Evidence map›Paper›PMID 32370791›Full record

ArticleBMC cardiovascular disorders2020

Toronto aortic stenosis quality of life questionnaire (TASQ): validation in TAVI patients.

Rima Styra, Michelle Dimas, Kathy Svitak, Mamta Kapoor, Mark Osten, Maral Ouzounian, Gerald Devins, Amy Deckert, Eric Horlick

Open access · goldAbstract readValidation Study
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  3. Observational
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rima StyraCenter for Mental Health, University Health Network, Toronto, Ontario, Canada. Rima.Styra@uhn.ca.
Michelle DimasCenter for Mental Health, University Health Network, Toronto, Ontario, Canada.
Kathy SvitakPeter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.
Mamta KapoorCenter for Mental Health, University Health Network, Toronto, Ontario, Canada.
Mark OstenPeter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.
Maral OuzounianPeter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.
Gerald DevinsCenter for Mental Health, University Health Network, Toronto, Ontario, Canada.
Amy DeckertCenter for Mental Health, University Health Network, Toronto, Ontario, Canada.
Eric HorlickPeter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.
University Health Network · CA

Funding

Edwards Lifesciences 410007511
6 · The paper itself

Abstract

backgroundAortic stenosis (AS) is a common cardiac condition whose prevalence increases with age. The symptom burden associated with severe aortic stenosis (AS) can introduce significant lifestyle disruptions and if left untreated can lead to a poor prognosis. Quality of life (QoL) is an important consideration in these patients. The TASQ is a QoL tool that was developed for aortic stenosis patients. We evaluated the psychometric properties of this specific questionnaire in patients who underwent transcatheter aortic valve implantation (TAVI), which is a therapeutic option for patients with severe aortic stenosis (AS).

methodsThe properties of the TASQ in measuring QoL were evaluated in AS patients undergoing TAVI. Patients presenting for the TAVI procedure (N = 62) were evaluated pre-TAVI, at discharge, 1-month, and 3-month follow-ups. Demographic information as well as caregiver status, and daily activities were recorded. In addition to the TASQ, they completed the KCCQ (Kansas City Cardiomyopathy Questionnaire) and the IIRS (Illness Intrusiveness Rating Scale).

resultsThe TASQ is a 16-item self-administered questionnaire that assesses AS-specific QoL across five domains: physical symptoms; physical limitations; emotional impact; social limitations, and health expectations. TASQ subscales are internally consistent (α = 0.74-0.96) and showed significant improvements from baseline across assessments (p < 0.001). Construct validity evidence was demonstrated by correlations consistent with theoretically derived hypotheses across time points.

conclusionsThe TASQ is a brief measure of AS-specific QoL that is sensitive to change in patients undergoing TAVI. Items on the TASQ capture important QoL concerns reported by AS patients, suggesting this is a measure of relevant and meaningful outcomes for this patient population. Detection of early improvements in QoL by the TASQ is promising, with important implications for the evaluation of procedural outcomes in this population.

Indexed as

Patient Reported Outcome MeasuresQuality of LifeTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic Valve StenosisFemaleHumansMalePredictive Value of TestsPsychometricsRecovery of FunctionReproducibility of ResultsTime FactorsTreatment OutcomeAortic stenosisPatient-reported outcome measurementQuality of lifeTAVI

Identifiers

PMID32370791
PMCPMC7201733
OpenAlexW3023593358

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.