Evidence map›Paper›PMID 32370610›Full record

ArticleJournal of medical screening2021

Early detection of breast cancer rectifies inequality of breast cancer outcomes.

László Tabár, Tony Hsiu-Hsi Chen, Amy Ming-Fang Yen, Peter B Dean, Robert A Smith, Håkan Jonsson, Sven Törnberg, Sam Li-Sheng Chen, Sherry Yueh-Hsia Chiu, Jean Ching-Yuan Fann and 24 more

Abstract read
In one paragraph

Article in Journal of medical screening, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Long-Term Performance of an Image-Based Short-Term Risk Model for Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

László TabárFalun Central Hospital, Falun, Sweden.
Tony Hsiu-Hsi ChenNational Taiwan University, Taipei City.
Amy Ming-Fang YenTaipei Medical University, Taipei City.
Peter B DeanDepartment of Diagnostic Radiology, University of Turku, Turku, Finland.
Robert A SmithAmerican Cancer Society, Atlanta, GA, USA.
Håkan JonssonDepartment of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden.
Sven TörnbergRegional Cancer Center Stockholm Gotland, Stockholm, Sweden.
Sam Li-Sheng ChenTaipei Medical University, Taipei City.
Sherry Yueh-Hsia ChiuChang Gung University, Taoyuan City.
Jean Ching-Yuan FannKainan University, Taoyuan City.
May Mei-Sheng KuNational Taiwan University, Taipei City.
Wendy Yi-Ying WuDepartment of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden.
Chen-Yang HsuNational Taiwan University, Taipei City.
Yu-Ching ChenNational Taiwan University, Taipei City.
Gunilla SvaneRegional Cancer Center Stockholm Gotland, Stockholm, Sweden.
Edward AzavedoRegional Cancer Center Stockholm Gotland, Stockholm, Sweden.
Helene GrundströmDanderyd Hospital, Danderyd, Sweden.
Per SundénDanderyd Hospital, Danderyd, Sweden.
Karin LeiflandSankt Göran Hospital, Stockholm, Sweden.
Ewa FrodisVästerås Central Hospital, Västerås, Sweden.
Joakim RamosVästerås Central Hospital, Västerås, Sweden.
Birgitta EpsteinÖrebro University Hospital, Örebro, Sweden.
Anders ÅkerlundCentral Hospital, Gävle, Sweden.
Ann SundbomKarlstad Central Hospital, Karlstad, Sweden.
Pál BordásSunderby Hospital, Department of Radiology, Norrbotten County, Sweden.
Hans WallinSundsvall Hospital, Sundsvall, Sweden.
Leena StarckSundsvall Hospital, Sundsvall, Sweden.
Annika BjörkgrenNorrlands University Hospital, Umeå, Sweden.
Stina CarlsonNorrlands University Hospital, Umeå, Sweden.
Irma FredrikssonRegional Cancer Center Stockholm Gotland, Stockholm, Sweden.
Johan AhlgrenRegional Cancer Center, Uppsala University Hospital, Uppsala, Sweden.
Daniel ÖhmanRegional Cancer Center Stockholm Gotland, Stockholm, Sweden.
Lars HolmbergUppsala University, Uppsala, Sweden and Translational Oncology & Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
Stephen W DuffyWolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.ORCID 0000-0003-4901-7922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explain apparent differences among mammography screening services in Sweden using individual data on participation in screening and with breast cancer-specific survival as an outcome.

methodsWe analysed breast cancer survival data from the Swedish Cancer Register on breast cancer cases from nine Swedish counties diagnosed in women eligible for screening. Data were available on 38,278 breast cancers diagnosed and 4312 breast cancer deaths. Survival to death from breast cancer was estimated using the Kaplan-Meier estimate, for all cases in each county, and separately for cases of women participating and not participating in their last invitation to screening. Formal statistical comparisons of survival were made using proportional hazards regression.

resultsAll counties showed a reduction in the hazard of breast cancer death with participation in screening, but the reductions for individual counties varied substantially, ranging from 51% (95% confidence interval 46-55%) to 81% (95% confidence interval 74-85%). Survival rates in nonparticipating women ranged from 53% (95% confidence interval 40-65%) to 74% (95% confidence interval 72-77%), while the corresponding survival in women participating in screening varied from 80% (95% confidence interval 77-84%) to 86% (95% confidence interval 83-88%), a considerably narrower range.

conclusionsDifferences among counties in the effect of screening on breast cancer outcomes were mainly due to variation in survival in women not participating in screening. Screening conferred similarly high survival rates in all counties. This indicates that the performance of screening services was similar across counties and that detection and treatment of breast cancer in early-stage reduces inequalities in breast cancer outcome.

Indexed as

Early Detection of CancerMammographyAdultAgedBreast NeoplasmsFemaleHumansKaplan-Meier EstimateMiddle AgedRegistriesSurvival RateSwedenTime FactorsBreast cancer, breast cancer screening, early detection, breast cancer survival

Identifiers

PMID32370610
PMCPMC7905745

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.