Evidence map›Paper›PMID 32370307›Full record

ArticleMarine drugs2020

Bengamide Analogues Show A Potent Antitumor Activity against Colon Cancer Cells: A Preliminary Study.

Beatriz García-Pinel, Cristina Porras-Alcalá, Laura Cabeza, Raul Ortiz, José Prados, Consolación Melguizo, Iván Cheng-Sánchez, Juan Manuel López-Romero, Francisco Sarabia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Total Synthesis of 4-Molecules (Basel, Switzerland) · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Beatriz García-PinelInstitute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada 18100, Spain.
Cristina Porras-AlcaláDepartment of Organic Chemistry, Faculty of Sciences, University of Malaga, Málaga 29071, Spain.
Laura CabezaInstitute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada 18100, Spain.
Raul OrtizInstitute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada 18100, Spain.
José PradosInstitute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada 18100, Spain.
Consolación MelguizoInstitute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada 18100, Spain.
Iván Cheng-SánchezDepartment of Organic Chemistry, Faculty of Sciences, University of Malaga, Málaga 29071, Spain.
Juan Manuel López-RomeroDepartment of Organic Chemistry, Faculty of Sciences, University of Malaga, Málaga 29071, Spain.
Francisco SarabiaDepartment of Organic Chemistry, Faculty of Sciences, University of Malaga, Málaga 29071, Spain.
Universidad de Granada · ESUniversidad de Málaga · ES

Funding

Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía BIO-267Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía CTS-107Consejería de Salud, Junta de Andalucía PI0102-2017Instituto de Salud Carlos III PI19/01478Ministerio de Economía, Industria y Competitividad, Gobierno de España BIO2014-56092-RMinisterio de Economía, Industria y Competitividad, Gobierno de España CTQ2016-73311Ministerio de Economía, Industria y Competitividad, Gobierno de España RTI2018-098296-BI00
6 · The paper itself

Abstract

The limited success and side effects of the current chemotherapeutic strategies against colorectal cancer (CRC), the third most common cancer worldwide, demand an assay with new drugs. The prominent antitumor activities displayed by the bengamides (Ben), a family of natural products isolated from marine sponges of the

Indexed as

PoriferaAnimalsAntineoplastic AgentsAzepinesCell Line, TumorColonic NeoplasmsDrug Screening Assays, AntitumorHumansStructure-Activity RelationshipAntineoplastic AgentsAzepinesbengamide Banaloguesantitumor agentsbengamidescolorectal cancersynthesis

Identifiers

PMID32370307
PMCPMC7281506
OpenAlexW3021498695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.