Evidence map›Paper›PMID 32370213›Full record

ArticleMolecules (Basel, Switzerland)2020

Phenylpyrazalopyrimidines as Tyrosine Kinase Inhibitors: Synthesis, Antiproliferative Activity, and Molecular Simulations.

Bhupender S Chhikara, Sajda Ashraf, Saghar Mozaffari, Nicole St Jeans, Dindyal Mandal, Rakesh Kumar Tiwari, Zaheer Ul-Haq, Keykavous Parang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  8. Src Mediates Epigallocatechin-3-Molecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Bhupender S ChhikaraDepartment of Chemistry, Aditi Mahavidyalaya, University of Delhi, Bawana, Delhi 110039, India.
Sajda AshrafDr. Panjwani Center for Molecular Medicine and Drug Research, ICCBS, University of Karachi, Karachi 75210, Pakistan.
Saghar MozaffariCenter For Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, California, Irvine, CA 92618, USA.
Nicole St JeansDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Rhode Island, Kingston, RI 02881, USA.
Dindyal MandalDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Rhode Island, Kingston, RI 02881, USA.
Rakesh Kumar TiwariDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Rhode Island, Kingston, RI 02881, USA.ORCID 0000-0003-3701-4548
Zaheer Ul-HaqDr. Panjwani Center for Molecular Medicine and Drug Research, ICCBS, University of Karachi, Karachi 75210, Pakistan.ORCID 0000-0002-8530-8711
Keykavous ParangDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Rhode Island, Kingston, RI 02881, USA.ORCID 0000-0001-8600-0893
Target (United States) · USUniversity of Karachi · PKUniversity of Delhi · INUniversity of Rhode Island · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsCell Line, TumorChemistry Techniques, SyntheticDose-Response Relationship, DrugEnzyme ActivationHumansMolecular ConformationMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructureProtein Kinase InhibitorsPyrimidinessrc-Family KinasesStructure-Activity RelationshipAntineoplastic AgentsProtein Kinase InhibitorsPyrimidinessrc-Family Kinasesantiproliferative activityenzyme inhibitionmolecular simulationphenylpyrazolopyrimidineprotein kinase

Identifiers

PMID32370213
PMCPMC7249037
OpenAlexW3023096242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.