Evidence map›Paper›PMID 32370017›Full record

ArticleMolecules (Basel, Switzerland)2020

Hybrid Imaging Agents for Pretargeting Applications Based on Fusarinine C-Proof of Concept.

Dominik Summer, Milos Petrik, Sonja Mayr, Martin Hermann, Piriya Kaeopookum, Joachim Pfister, Maximilian Klingler, Christine Rangger, Hubertus Haas, Clemens Decristoforo

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Metal-Based Radiopharmaceuticals in Inorganic Chemistry.Molecules (Basel, Switzerland) · 2023
    Article
  5. Radiometal chelators for infection diagnostics.Frontiers in nuclear medicine · 2023
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Dominik SummerDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-1352-5370
Milos PetrikInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, 772-00 Olomouc, Czech Republic.ORCID 0000-0003-1334-5916
Sonja MayrDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.
Martin HermannDepartment of Anaesthesia and Intensive Care, Medical University Innsbruck, A-6020 Innsbruck, Austria.
Piriya KaeopookumDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.
Joachim PfisterDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.
Maximilian KlinglerDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-8499-9434
Christine RanggerDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0003-1167-9779
Hubertus HaasInstitute of Molecular Biology, Medical University Innsbruck, A-6020 Innsbruck, Austria.
Clemens DecristoforoDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0003-0566-4036
Innsbruck Medical University · ATInstitute of Molecular and Translational Medicine · CZ

Funding

Austrian Science Fund FWF P 25899
6 · The paper itself

Abstract

Hybrid imaging combining the beneficial properties of radioactivity and optical imaging within one imaging probe has gained increasing interest in radiopharmaceutical research. In this study, we modified the macrocyclic gallium-68 chelator fusarinine C (FSC) by conjugating a fluorescent moiety and tetrazine (Tz) moieties. The resulting hybrid imaging agents were used for pretargeting applications utilizing click reactions with a

Indexed as

Ferric CompoundsHydroxamic AcidsMultimodal ImagingRadiopharmaceuticalsClick ChemistryFluorescent Antibody TechniqueGallium RadioisotopesOptical ImagingPositron-Emission TomographyProof of Concept StudyRadioisotopesTissue DistributionFerric CompoundsfusigenGallium-68Gallium RadioisotopesHydroxamic AcidsRadioisotopesRadiopharmaceuticalsclick chemistryfluorescencefusarinine Cgallium-68optical imagingPET

Identifiers

PMID32370017
PMCPMC7249120
OpenAlexW3023931351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.