ArticlePolymers2020
Development of a Highly Proliferated Bilayer Coating on 316L Stainless Steel Implants.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 56 citations in OpenAlex.
- Graphene oxide coating on two-dimensional glass substrates and three-dimensional zirconia scaffolds for bone tissue regeneration.Materials today. Bio · 2026Article
- Polycatecholamine nanocoatings on stainless steel: the effect on attachment of human fibroblasts and platelets.Beilstein journal of nanotechnology · 2026Article
- The facile conversion of waste biomass into few-layer graphene oxide.Scientific reports · 2025Article
- Advances in Multifunctional Bioactive Coatings for Metallic Bone Implants.Materials (Basel, Switzerland) · 2022Review
- Design and Validation of Additively Manufactured Metallic Cellular Scaffold Structures for Bone Tissue Engineering.Materials (Basel, Switzerland) · 2022Article
- Development of Graphene-Based Materials in Bone Tissue Engineaering.Global challenges (Hoboken, NJ) · 2022Review
- A state-of-the-art review of the fabrication and characteristics of titanium and its alloys for biomedical applications.Bio-design and manufacturing · 2022Review
- Analytical Techniques for the Characterization of Bioactive Coatings for Orthopaedic Implants.Biomedicines · 2021Review
- Physicochemical and Biological Properties of Graphene-Oxide-Coated Metallic Materials.Materials (Basel, Switzerland) · 2021Article
- Multifunctional and Self-Healable Intelligent Hydrogels for Cancer Drug Delivery and Promoting Tissue Regeneration In Vivo.Polymers · 2021Review
- In Vitro and In Vivo Characterization of PLLA-316L Stainless Steel Electromechanical Devices for Bone Tissue Engineering-A Preliminary Study.International journal of molecular sciences · 2021Article
- Effects of water absorption on the mechanical properties of hybrid natural fibre/phenol formaldehyde composites.Scientific reports · 2021Article
- Bioactive Coatings with Ag-Camphorimine Complexes to Prevent Surface Colonization by the Pathogenic YeastAntibiotics (Basel, Switzerland) · 2021Article
- The Effect of Poly (Ethylene glycol) Emulation on the Degradation of PLA/Starch Composites.Polymers · 2021Article
- Thermal Degradation Kinetics and Modeling Study of Ultra High Molecular Weight Polyethylene (UHMWP)/Graphene Nanocomposite.Molecules (Basel, Switzerland) · 2021Article
- Electrospun Scaffold of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration.Journal of bionic engineering · 2021Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this research, a bilayer coating has been applied on the surface of 316 L stainless steel (316LSS) to provide highly proliferated metallic implants for bone regeneration. The first layer was prepared using electrophoretic deposition of graphene oxide (GO), while the top layer was coated utilizing electrospinning of poly (ε-caprolactone) (PCL)/gelatin (Ge)/forsterite solutions. The morphology, porosity, wettability, biodegradability, bioactivity, cell attachment and cell viability of the prepared coatings were evaluated. The Field Emission Scanning Electron Microscopy (FESEM) results revealed the formation of uniform, continuous, and bead-free nanofibers. The Energy Dispersive X-ray (EDS) results confirmed well-distributed forsterite nanoparticles in the structure of the top coating. The porosity of the electrospun nanofibers was found to be above 70%. The water contact angle measurements indicated an improvement in the wettability of the coating by increasing the amount of nanoparticles. Furthermore, the electrospun nanofibers containing 1 and 3 wt.% of forsterite nanoparticles showed significant bioactivity after soaking in the simulated body fluid (SBF) solution for 21 days. In addition, to investigate the in vitro analysis, the MG-63 cells were cultured on the PCL/Ge/forsterite and GO-PCL/Ge/forsterite coatings. The results confirmed an excellent cell adhesion along with considerable cell growth and proliferation. It should be also noted that the existence of the forsterite nanoparticles and the GO layer substantially enhanced the cell proliferation of the coatings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.