ArticleNutrients2020
Long-Term Coffee Consumption is Associated with Fecal Microbial Composition in Humans.
Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Association between different drinks consumption and risk of inflammatory bowel disease: a dose-response meta-analysis.Frontiers in nutrition · 2026Pooled it
- The Effectiveness of Caffeine in Reducing Constipation in Adults: A Systematic Review.International urogynecology journal · 2025Pooled it
- Effects of short-term, high-dose cocoa-derived flavanol supplementation on gut microbiota composition: secondary findings from a randomized, double-blind, placebo-controlled crossover study.Journal of nutritional science · 2024Trial
- Trial
- Coffee, the Gut Microbiome, and Host Metabolism: Gastrointestinal Fate, Microbial Transformation, Mechanistic Insights, and Prospects for Precision Nutrition.Metabolites · 2026Review
- Association of coffee intake with risk of all-cause and colorectal cancer-specific mortality among individuals with colorectal cancer in the Multiethnic Cohort Study.Cancer causes & control : CCC · 2026Article
- Plant-Derived Foods and Medicines as Modulators of the Gut Microbiome: Molecular Interactions and Implications for Disease and Therapy.Molecules (Basel, Switzerland) · 2026Review
- Caffeine and Headache: Exploring the Multifaceted Relationship.Brain and behavior · 2026Review
- Bioactive Compounds in Coffee: Metabolism, Bioavailability and Health Effects-A Review.Molecules (Basel, Switzerland) · 2026Review
- Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition.Nature communications · 2026Article
- Anti-Obesogenic Effects of Culinary Herbs Through Modulation of Inflammation and Metabolic Pathways.Nutrients · 2026Review
- Microbiota-targeted therapeutic strategies for elderly-onset rheumatoid arthritis: based on the gut-joint axis.Frontiers in immunology · 2026Review
- The impact of caffeine-mediated gut microbiota regulation on the athletic performance of football players.Biology of sport · 2026Article
- Phenome-wide associations of coffee intake in the human phenotype project.Metabolism: clinical and experimental · 2026Article
- Antimicrobial potentials and challenges of paracetamol: A comprehensive reassessment based on database reports.Pharmaceutical science advances · 2025Review
- Long-term follow-up study on the impact of a gut microbiota-supportive diet on heart failure and mortality outcomes.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Effects of Athletic Nutritional Supplements on the Human Gut Microbiota: A Narrative Review.Nutrients · 2025Review
- Exploring the Role of Oral Microbiota in the Pathophysiology and Treatment of Bruxism.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Review
- Association of dietary caffeine intake and metabolites in the urine of individuals with latent tuberculosis infection: a cross-sectional study.BMC pulmonary medicine · 2025Article
- Coffee Consumption and Mortality among United States Adults: A Prospective Cohort Study.The Journal of nutrition · 2025Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Coffee consumption has been related to a preventive effect against several non-transmissible pathologies. Due to the content of this beverage in phytochemicals and minerals, it has been proposed that its impact on health may partly depend on gut microbiota modulation. Our aim was to explore the interaction among gut microbiota, fecal short chain fatty acids, and health-related parameters in 147 healthy subjects classified according to coffee consumption, to deepen the association of the role of the (poly)phenol and alkaloid content of this beverage. Food daily intake was assessed by an annual food frequency questionnaire (FFQ). Coffee consumption was categorized into three groups: non-coffee-consumers (0-3 mL/day), moderate consumers (3-45 mL/day) and high-coffee consumers (45-500 mL/day). Some relevant groups of the gut microbiota were determined by qPCR, and concentration of fecal short chain fatty acids by gas chromatography. Serum health related biomarkers were determined by standardized methods. Interestingly, a higher level of
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.