ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2020
Multiparametric mapping of white matter microstructure in catatonia.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Functional neuroimaging in patients with catatonia: A systematic review.Journal of psychosomatic research · 2024Pooled it
- [The sensorimotor domain in the research domain criteria system: progress and perspectives].Der Nervenarzt · 2021Pooled it
- Implementation and validation of a clinically compatible four-shell diffusion MRI protocol for ischemic stroke research.MethodsX · 2026Article
- Schizophrenia and disordered sensorimotor control: challenges, mechanisms and opportunities.Brain : a journal of neurology · 2026Review
- Anterior Superior Longitudinal Fasciculus Microstructure Correlates With Bimanual Visuomotor Performance in Healthy Younger but Not Older Adults.The European journal of neuroscience · 2026Article
- Delineating white matter phenotypes of sensori-/psychomotor functioning in large-scale cohorts of healthy individuals and patients with mental disorders across the lifespan (whiteSPAN): rationale and methods of an interdisciplinary bicentric project.European archives of psychiatry and clinical neuroscience · 2026Article
- Neurobiological and psychological indicators of post-traumatic stress symptoms in children and adolescents treated for a posterior fossa brain tumour.Neuroimage. Reports · 2026Article
- Personalized White Matter Bundle Segmentation for Early Childhood.Proceedings of SPIE--the International Society for Optical Engineering · 2026Article
- Frontal-striatal-thalamic circuit dysfunction and inferential processing between internal representations and external events across the psychosis spectrum.Frontiers in psychiatry · 2026Review
- Sensitivity of quantitative diffusion MRI tractography and microstructure to anisotropic spatial sampling.Magnetic resonance imaging · 2025Article
- White matter microstructural and macrostructural profiles during midlife reveal sex differences between men and women at different menopausal stages.Scientific reports · 2025Article
- Myelin water and tensor-valued diffusion imaging: (How) are they related?Magnetic resonance in medicine · 2025Article
- CATATOnia treatment with transcranial direct current electrostimulation: protocol of a randomised, double-blind, placebo-controlled bicentric superiority study (CATATOES).BMC psychiatry · 2025Article
- Deciphering white matter microstructural alterations in catatonia according to ICD-11: replication and machine learning analysis.Molecular psychiatry · 2025Article
- An Investigation of Corticospinal Tract Microstructural Integrity in ARSACS Using a Profilometry MRI Analysis: Results From the PROSPAX Study.European journal of neurology · 2025Article
- Common and unique white matter fractional anisotropy patterns in patients with schizophrenia with medication-resistant auditory verbal hallucinations: a retrospective tract-based spatial statistics study.Schizophrenia (Heidelberg, Germany) · 2025Article
- Sensori- and psychomotor abnormalities, psychopathological symptoms and functionality in schizophrenia-spectrum disorders: a network analytic approach.Schizophrenia (Heidelberg, Germany) · 2025Article
- Longitudinal investigation of neurobiological changes across pregnancy.Communications biology · 2025Article
- White matter microstructure of language pathways in non-verbal autism: insights from diffusion tensor imaging and myelin water imaging.Frontiers in human neuroscience · 2025Article
- Anterograde and trans-synaptic neurodegeneration in aquaporin-4-antibody neuromyelitis optica spectrum disorder patients with a history of transverse myelitis.Brain communications · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Catatonia is characterized by motor, affective and behavioral abnormalities. To date, the specific role of white matter (WM) abnormalities in schizophrenia spectrum disorders (SSD) patients with catatonia is largely unknown. In this study, diffusion magnetic resonance imaging (dMRI) data were collected from 111 right-handed SSD patients and 28 healthy controls. Catatonic symptoms were examined on the Northoff Catatonia Rating Scale (NCRS). We used whole-brain tract-based spatial statistics (TBSS), tractometry (along tract statistics using TractSeg) and graph analytics (clustering coefficient-CCO, local betweenness centrality-BC) to provide a framework of specific WM microstructural abnormalities underlying catatonia in SSD. Following a categorical approach, post hoc analyses showed differences in fractional anisotrophy (FA) measured via tractometry in the corpus callosum, corticospinal tract and thalamo-premotor tract as well as increased CCO as derived by graph analytics of the right superior parietal cortex (SPC) and left caudate nucleus in catatonic patients (NCRS total score ≥ 3; n = 30) when compared to non-catatonic patients (NCRS total score = 0; n = 29). In catatonic patients according to DSM-IV-TR (n = 43), catatonic symptoms were associated with FA variations (tractometry) of the left corticospinal tract and CCO of the left orbitofrontal cortex, primary motor cortex, supplementary motor area and putamen. This study supports the notion that structural reorganization of WM bundles connecting orbitofrontal/parietal, thalamic and striatal regions contribute to catatonia in SSD patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.