Evidence map›Paper›PMID 32369601›Full record

ArticleNeuro-oncology2020

Neuro-oncology Management During the COVID-19 Pandemic With a Focus on WHO Grade III and IV Gliomas.

Denise Bernhardt, Wolfgang Wick, Stephanie E Weiss, Arjun Sahgal, Simon S Lo, John H Suh, Eric L Chang, Matthew Foote, James Perry, Bernhard Meyer and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Neuro-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

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  19. How has the COVID-19 pandemic impacted clinical care and research in Neuro-Oncology?Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2022
    Review
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 4 countries.

Denise BernhardtTechnical University of Munich (TUM), School of Medicine and Klinikum rechts der Isar, Department of Radiation Oncology, Munich.
Wolfgang WickNeurology Clinic, University of Heidelberg and German Cancer Research Center, Heidelberg, Germany.
Stephanie E WeissFox Chase Cancer Center, Philadelphia, Pennsylvania.
Arjun SahgalDepartment of Radiation Oncology, Sunnybrook Health Science Centre, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
Simon S LoDepartment of Radiation Oncology, University of Washington School of Medicine, Seattle, Washington, USA.
John H SuhDepartment of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Eric L ChangDepartment of Radiation Oncology, Keck School of Medicine at University of Southern California, Los Angeles, California, USA.
Matthew FooteDepartment of Radiation Oncology, Princess Alexandra Hospital, University of Queensland, Woolloongabba, QLD, Australia.
James PerryDivision of Neurology, Department of MedicineOdette Cancer and Sunnybrook Health Science Centres, University of Toronto, Canada.
Bernhard MeyerTechnical University of Munich (TUM), School of Medicine and Klinikum rechts der Isar, Department of Neurosurgery, Munich.
Peter VajkoczyDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Berlin, Germany.
Patrick Y WenCenter for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts, USA.
Christoph StraubeTechnical University of Munich (TUM), School of Medicine and Klinikum rechts der Isar, Department of Radiation Oncology, Munich.
Steffi PigorschTechnical University of Munich (TUM), School of Medicine and Klinikum rechts der Isar, Department of Radiation Oncology, Munich.
Jan J WilkensTechnical University of Munich (TUM), School of Medicine and Klinikum rechts der Isar, Department of Radiation Oncology, Munich.
Stephanie E CombsTechnical University of Munich (TUM), School of Medicine and Klinikum rechts der Isar, Department of Radiation Oncology, Munich.
TUM Klinikum · DESunnybrook Health Science Centre · CACenter for Neuro-Oncology · USCharité - Universitätsmedizin Berlin · DECleveland Clinic · USFox Chase Cancer Center · USGerman Cancer Research Center · DEThe University of Queensland · AUUniversity of Southern California · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBecause of the increased risk in cancer patients of developing complications caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), physicians have to balance the competing risks of the negative impact of the pandemic and the primary tumor. In this consensus statement, an international group of experts present mitigation strategies and treatment guidance for patients suffering from high grade gliomas (HGG) during the coronavirus disease 2019 (COVID-19) pandemic. METHOD /

results16 international experts in the treatment of HGG contributed to this consensus-based practice recommendation including neuro-oncologists, neurosurgeons, radiation -oncologists and a medical physicist. Generally, treatment of neuro-oncological patients cannot be significantly delayed and initiating therapy should not be outweighed by COVID-19. We present detailed interdisciplinary treatment strategies for molecular subgroups in two pandemic scenarios, a scale-up phase and a crisis phase.

conclusionThis practice recommendation presents a pragmatic framework and consensus-based mitigation strategies for the treatment of HGG patients during the SARS-CoV-2 pandemic.

Indexed as

COVID-19glioblastomahigh-grade gliomaneuro-oncologySARS-CoV-2

Identifiers

PMID32369601
PMCPMC7239150
OpenAlexW3021575924

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.