Evidence map›Paper›PMID 32369438›Full record

ArticleeLife2020

Protein phosphatase 1 activity controls a balance between collective and single cell modes of migration.

Yujun Chen, Nirupama Kotian, George Aranjuez, Lin Chen, C Luke Messer, Ashley Burtscher, Ketki Sawant, Damien Ramel, Xiaobo Wang, Jocelyn A McDonald

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Finishing the egg.Genetics · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. TheMolecular biology of the cell · 2022
    Article
  7. Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yujun ChenDivision of Biology, Kansas State University, Manhattan, United States.ORCID 0000-0003-3190-6713
Nirupama KotianDivision of Biology, Kansas State University, Manhattan, United States.
George AranjuezLerner Research Institute, Cleveland Clinic, Cleveland, United States.
Lin ChenLBCMCP, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
C Luke MesserDivision of Biology, Kansas State University, Manhattan, United States.
Ashley BurtscherLerner Research Institute, Cleveland Clinic, Cleveland, United States.
Ketki SawantDivision of Biology, Kansas State University, Manhattan, United States.
Damien RamelLBCMCP, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.ORCID 0000-0002-9089-1497
Xiaobo WangLBCMCP, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Jocelyn A McDonaldDivision of Biology, Kansas State University, Manhattan, United States.ORCID 0000-0002-7494-1466
Kansas State University · USCentre National de la Recherche Scientifique · FRCleveland Clinic Lerner College of Medicine · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SUSAN J. BROWN · 2012 to 2026
$63.0M
ARC Foundation for Cancer Research PJA20191209714National Science Foundation 1456053National Science Foundation 1738757NIGMS NIH HHS P20 GM103418
6 · The paper itself

Abstract

Collective cell migration is central to many developmental and pathological processes. However, the mechanisms that keep cell collectives together and coordinate movement of multiple cells are poorly understood. Using the

Indexed as

AnimalsCell MovementDrosophila melanogasterDrosophila ProteinsFemaleGenesMaleProtein Phosphatase 1Drosophila ProteinsProtein Phosphatase 1cell adhesioncell biologycell collectivecell migrationdevelopmental biologyD. melanogastermyosinprotein phosphatases

Identifiers

PMID32369438
PMCPMC7200163
OpenAlexW3021444533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.