Evidence map›Paper›PMID 32369393›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Mild to Moderate Sleep Apnea Is Linked to Hypoxia-induced Motor Recovery after Spinal Cord Injury.

Isabelle Vivodtzev, Andrew Q Tan, Megan Hermann, Arun Jayaraman, Victoria Stahl, William Zev Rymer, Gordon S Mitchell, Heather B Hayes, Randy D Trumbower

2 registry-linked trialsAbstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05217498 phase1 / phase2not yet recruitingnot on this mapstarted 2027, after this paper: background citation

A Selective Adenosine 2a Antagonist to Enhance Training-related Gains in Walking Function for Persons With Chronic, Incomplete Spinal Cord Injury

TypeinterventionalSponsorRandy Trumbower, PT, PhDRan2027 to 2028Enrolled40ConditionsSpinal Cord Injuries, MyelopathyArmsIstradefylline, low oxygen therapy
NCT05377424 phase1 / phase2active not recruitingnot on this mapstarted 2022, after this paper: background citation

Acute Adenosine Receptor Antagonism to Promote Breathing Plasticity in ALS

TypeinterventionalSponsorUniversity of FloridaRan2022 to 2026Enrolled40ConditionsALSArmsConsume 20mg of istradefylline, Low Oxygen therapy, Placebo counterpart to the istradefylline drug, SHAM counterpart to low oxygen therapy.
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  14. The role of lncRNA-MEG/miR-21-5p/PDCD4 axis in spinal cord injury.American journal of translational research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Isabelle VivodtzevHarvard Medical School Boston, Massachusetts.ORCID 0000-0002-5201-8603
Andrew Q TanHarvard Medical School Boston, Massachusetts.
Megan HermannShirley Ryan AbilityLab Chicago, Illinois.
Arun JayaramanShirley Ryan AbilityLab Chicago, Illinois.
Victoria StahlEmory University School of Medicine Atlanta, Georgia and.
William Zev RymerShirley Ryan AbilityLab Chicago, Illinois.
Gordon S MitchellUniversity of Florida Gainesville, Florida.
Heather B HayesEmory University School of Medicine Atlanta, Georgia and.
Randy D TrumbowerHarvard Medical School Boston, Massachusetts.ORCID 0000-0002-2282-9974

Funding

Mechanisms of intermittent hypoxia-induced motor recovery in persons with SCIR01HD081274 · NICHD · SPAULDING REHABILITATION HOSPITAL · PI TRUMBOWER, RANDY D · 2014 to 2018
$2.4M
NICHD NIH HHS R01 HD081274
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultFemaleHumansHypoxiaMaleMiddle AgedMotor ActivityOxygen Inhalation TherapyRecovery of FunctionSleep Apnea SyndromesSpinal Cord Injuries

Identifiers

PMID32369393
PMCPMC7491397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.