Evidence map›Paper›PMID 32369369›Full record

ArticleNano letters2020

High-Resolution Photonic Force Microscopy Based on Sharp Nanofabricated Tips.

Rudy Desgarceaux, Zhanna Santybayeva, Eliana Battistella, Ashley L Nord, Catherine Braun-Breton, Manouk Abkarian, Onofrio M Maragò, Benoit Charlot, Francesco Pedaci

Open access · greenAbstract read
In one paragraph

Article in Nano letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Optical Tweezers Exploring Neuroscience.Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Rudy DesgarceauxCBS Un.Montpellier, CNRS, INSERM, Montpellier 34090, France.
Zhanna SantybayevaCBS Un.Montpellier, CNRS, INSERM, Montpellier 34090, France.
Eliana BattistellaCBS Un.Montpellier, CNRS, INSERM, Montpellier 34090, France.
Ashley L NordCBS Un.Montpellier, CNRS, INSERM, Montpellier 34090, France.
Catherine Braun-BretonUn.Montpellier, CNRS UMR 5235, Montpellier 34095, France.
Manouk AbkarianCBS Un.Montpellier, CNRS, INSERM, Montpellier 34090, France.
Onofrio M MaragòCNR-IPCF, Istituto per i Processi Chimico-Fisici, Messina 98158, Italy.
Benoit CharlotIES, CNRS University of Montpellier, Montpellier 34095, France.ORCID 0000-0001-7178-1949
Francesco PedaciCBS Un.Montpellier, CNRS, INSERM, Montpellier 34090, France.ORCID 0000-0002-4530-3027
Centre National de la Recherche Scientifique · FRInstitute for Chemical and Physical Processes · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although near-field imaging techniques reach sub-nanometer resolution on rigid samples, it remains extremely challenging to image soft interfaces, such as biological membranes, due to the deformations induced by the probe. In photonic force microscopy, optical tweezers are used to manipulate and measure the scanning probe, allowing imaging of soft materials without force-induced artifacts. However, the size of the optically trapped probe still limits the maximum resolution. Here, we show a novel and simple nanofabrication protocol to massively produce optically trappable quartz particles which mimic the sharp tips of atomic force microscopy. Imaging rigid nanostructures with our tips, we resolve features smaller than 80 nm. Scanning the membrane of living malaria-infected red blood cells reveals, with no visible artifacts, submicron features termed knobs, related to the parasite activity. The use of nanoengineered particles in photonic force microscopy opens the way to imaging soft samples at high resolution.

Indexed as

malariaoptical tweezersphotonic force microscopyred blood cellssharp nanocylinders

Identifiers

PMID32369369
PMCPMC7292031
OpenAlexW3004831266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.