ArticleGigaScience2020
Antibiotic resistomes discovered in the gut microbiomes of Korean swine and cattle.
Article in GigaScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- An Overview of Antibiotic Resistance and Abiotic Stresses Affecting Antimicrobial Resistance in Agricultural Soils.International journal of environmental research and public health · 2022Pooled it
- Dynamics of Bacterial Communities and Resistomes Across Swine Waste Stabilization Ponds and Fertilized Soils.Current microbiology · 2026Article
- Implementation of a high-throughput microfluidic platform for antimicrobial resistance surveillance in swine production systems.Microbial genomics · 2026Article
- Intersite differences in gut microbiome are associated with habitat quality in a limestone forest-dwelling langur.BMC microbiology · 2026Article
- Effects of Age, Sex, and Social Network on Antibiotic Resistance Genes in the Gut Microbiome of Tibetan Macaques (Ecology and evolution · 2026Article
- Metagenomic analysis of fecal and environmental microbiota in rural mixed livestock farming systems in South Africa.Frontiers in cellular and infection microbiology · 2026Article
- The fecal resistome of beef cattle from conventional grain-fed and grass-fed systems in the Western United States.BMC microbiology · 2025Article
- Antibiotic Resistance Genes and Microbiota inJournal of agricultural and food chemistry · 2025Article
- Characterization of the diversity, genomic features, host bacteria, and distribution of crAss-like phages in the pig gut microbiome.Frontiers in veterinary science · 2025Article
- Seasonal stability of the rumen microbiome contributes to the adaptation patterns to extreme environmental conditions in grazing yak and cattle.BMC biology · 2024Article
- Antibiotic Resistance Genes in Global Food Transformation System: Edible Insects vs. Livestock.Foods (Basel, Switzerland) · 2024Article
- Daily occupational exposure in swine farm alters human skin microbiota and antibiotic resistome.iMeta · 2024Article
- Comparative analyses of the faecal resistome against β-lactam and quinolone antibiotics in humans and livestock using metagenomic sequencing.Scientific reports · 2023Article
- Metagenomic analysis of gut microbiome and resistome of Whooper and Black Swans: a one health perspective.BMC genomics · 2023Article
- Gut microbiome variations in Rhinopithecus roxellanae caused by changes in the environment.BMC genomics · 2023Article
- Antibiotic resistance profiles of gut microbiota across various primate species in Guangxi.Frontiers in microbiology · 2023Article
- Occupational exposure in swine farm defines human skin and nasal microbiota.Frontiers in microbiology · 2023Article
- A glance at the gut microbiota and the functional roles of the microbes based on marmot fecal samples.Frontiers in microbiology · 2023Article
- Importance of Microbiome of Fecal Samples Obtained from Adolescents with Different Weight Conditions on Resistance Gene Transfer.Microorganisms · 2022Article
- A global phylogenomic and metabolic reconstruction of the large intestine bacterial community of domesticated cattle.Microbiome · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibiotics administered to farm animals have led to increasing prevalence of resistance genes in different microbiomes and environments. While antibiotic treatments help cure infectious diseases in farm animals, the possibility of spreading antibiotic resistance genes into the environment and human microbiomes raises significant concerns. Through long-term evolution, antibiotic resistance genes have mutated, thereby complicating the resistance problems.
resultsIn this study, we performed deep sequencing of the gut microbiomes of 36 swine and 41 cattle in Korean farms, and metagenomic analysis to understand the diversity and prevalence of antibiotic resistance genes. We found that aminoglycoside, β-lactam, lincosamide, streptogramin, and tetracycline were the prevalent resistance determinants in both swine and cattle. Tetracycline resistance was abundant and prevalent in cattle and swine. Specifically, tetQ, tetW, tetO, tet32, and tet44 were the 5 most abundant and prevalent tetracycline resistance genes. Their prevalence was almost 100% in swine and cattle. While tetQ was similarly abundant in both swine and cattle, tetW was more abundant in swine than in cattle. Aminoglycoside was the second highest abundant resistance determinant in swine, but not in cattle. In particular, ANT(6) and APH(3'') were the dominant resistance gene families in swine. β-lactam was also an abundant resistance determinant in both swine and cattle. Cfx was the major contributing gene family conferring resistance against β-lactams.
conclusionsAntibiotic resistome was more pervasive in swine than in cattle. Specifically, prevalent antibiotic resistance genes (prevalence >50%) were found more in swine than in cattle. Genomic investigation of specific resistance genes from the gut microbiomes of swine and cattle in this study should provide opportunities to better understand the exchange of antibiotic resistance genes in farm animals.
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