ReviewMolecular genetics & genomic medicine2020
Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment.
Review in Molecular genetics & genomic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06207890 (An Analysis of Participation Trends), which is not on this map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Analysis of Participation Trends: Observing Patient Engagement in Anorexia Nervosa Clinical Trials
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- A Systematic Review to Explore a Neuropsychological Profile that Predates Anorexia Nervosa.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Pooled it
- Association of serotonin receptor gene polymorphisms with anorexia nervosa: a systematic review and meta-analysis.Eating and weight disorders : EWD · 2024Pooled it
- Genetic polymorphisms and their association with neurobiological and psychological factors in anorexia nervosa: a systematic review.Frontiers in psychology · 2024Pooled it
- Famine, plague, and slaughters: The fleeing famine hypothesis of anorexia nervosa reconsidered.Psychological review · 2026Article
- Neurogenesis and neuroplasticity activities of natural products: therapeutic potential in Alzheimer's disease.Frontiers in pharmacology · 2026Review
- Coordinated epigenetic dysregulation of CNR1 and FAAH genes drives endocannabinoid system dysfunction in anorexia nervosa.Journal of eating disorders · 2025Article
- Revealing the effects of various immune cells in anorexia nervosa: Evidence from Mendelian randomization.Medicine · 2025Article
- Parent-daughter emotional dyssynchrony correlates with personality and psychopathology in adolescents with anorexia nervosa.Eating and weight disorders : EWD · 2025Article
- Genetic Predisposition and Severity of Eating Disorders- A Review.CNS & neurological disorders drug targets · 2025Review
- Anorexia nervosa in children and adolescents: an early detection of risk factors.Italian journal of pediatrics · 2024Article
- Longitudinal Impact of Disordered Eating Attitudes on Depression, Anxiety, and Somatization in Young Women with Anorexia and Bulimia.Journal of clinical medicine · 2024Article
- Unexpected identification of obesity-associated mutations in LEP and MC4R genes in patients with anorexia nervosa.Scientific reports · 2024Article
- Neural Response to Expecting a Caloric Sweet Taste Stimulus Predicts Body Mass Index Longitudinally Among Young Adult Women With Anorexia Nervosa.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Potential applications of Schema Therapy in the treatment of adolescents with anorexia nervosa: a theoretical analysis.Postepy psychiatrii neurologii · 2023Review
- Natural compound targeting BDNF V66M variant: insights from in silico docking and molecular analysis.AMB Express · 2023Article
- Gender and sex in eating disorders: A narrative review of the current state of knowledge, research gaps, and recommendations.Brain and behavior · 2023Review
- Anorexia Nervosa in Adolescence: Parental Narratives Explore Causes and Responsibilities.International journal of environmental research and public health · 2023Article
- Article
- Genetic investigation of the contribution of body composition to anorexia nervosa in an electronic health record setting.Translational psychiatry · 2022Article
- A next generation sequencing gene panel for use in the diagnosis of anorexia nervosa.Eating and weight disorders : EWD · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnorexia nervosa is a multifactorial eating disorder that manifests with self-starvation, extreme anxiety, hyperactivity, and amenorrhea. Long-term effects include organ failure, disability, and in extreme cases, even death.
methodsThrough a literature search, here we summarize what is known about the molecular etiology of anorexia nervosa and propose genetic testing for this condition.
resultsAnorexia nervosa often has a familial background and shows strong heritability. Various genetic studies along with genome-wide association studies have identified several genetic loci involved in molecular pathways that might lead to anorexia.
conclusionAnorexia nervosa is an eating disorder with a strong genetic component that contributes to its etiology. Various genetic approaches might help in the molecular diagnosis of this disease and in devising novel therapeutic options.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.