Evidence map›Paper›PMID 32368717›Full record

ArticleJNCI cancer spectrum2020

Comparative Survival of Asian and White Metastatic Castration-Resistant Prostate Cancer Men Treated With Docetaxel.

Susan Halabi, Sandipan Dutta, Catherine M Tangen, Mark Rosenthal, Daniel P Petrylak, Ian M Thompson, Kim N Chi, Johann S De Bono, John C Araujo, Christopher Logothetis and 8 more

Open access · goldAbstract read
In one paragraph

Article in JNCI cancer spectrum, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Prostate cancer burden in South Asia: A systematic analysis of global burden of disease data (1990-2021).International journal of urology : official journal of the Japanese Urological Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 17 institutions in 5 countries.

Susan HalabiDepartment of Biostatistics and Bioinformatics, School of Medicine, Duke University, Durham, NC, USA.ORCID 0000-0003-4135-2777
Sandipan DuttaDepartment of Mathematics and Statistics, Old Dominion University, Norfolk, VA, USA.
Catherine M TangenPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Mark RosenthalDepartment of Medical Oncology, Peter MacCallum Cancer Centre, Parkville, Australia.
Daniel P PetrylakMedical Oncology, Yale School of Medicine, New Haven, CT, USA.
Ian M ThompsonPresident, Christus San Rosa Hospital Medical Center, San Antonio, TX, USA.
Kim N ChiMedical Oncology, British Columbia Cancer Agency - Vancouver Centre, Vancouver, BC, USA.
Johann S De BonoDivision of Clinical Studies, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
John C AraujoDepartment of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Christopher LogothetisDepartment of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Mario A EisenbergerOncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA.
David I QuinnGenitourinary Oncology, Department of Medicine University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
Karim FizaziMedical Oncology, Gustave Roussy, Villejuif, France.
Michael J MorrisGenitourinary Oncology Service, Department of Medicine. Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Celestia S HiganoDepartment of Medicine, University of Washington School of Medicine and Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Ian F TannockDepartment of Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Eric J SmallDepartment of Medicine, and University of California San Francisco Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
William Kevin KellyMedical Oncology and Urology, Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, PA, USA.
The University of Texas MD Anderson Cancer Center · USChristus Santa Rosa Health System · USDuke University · USFred Hutch Cancer Center · USInstitut Gustave Roussy · FRJohns Hopkins University · USMemorial Sloan Kettering Cancer Center · USOld Dominion University · USPeter MacCallum Cancer Centre · AURoyal Marsden NHS Foundation Trust · GBThomas Jefferson University · USUniversity of California, San Francisco · USUniversity of Southern California · USUniversity of Toronto · CAUniversity of Washington · USVancouver Clinic · USYale University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
SWOG Network Group Operations Center of the NCTNU10CA180888 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PRIMO N. LARA · 2014 to 2026
$152.1M
SWOG Statistics & Data Management Center complex - extension supplement for GY06U10CA180819 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Michael L. LeBlanc · 2014 to 2026
$115.2M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016672NCI NIH HHS U10 CA180819NCI NIH HHS U10 CA180888
6 · The paper itself

Abstract

There are few data regarding disparities in overall survival (OS) between Asian and white men with metastatic castration-resistant prostate cancer (mCRPC). We compared OS of Asian and white mCRPC men treated in phase III clinical trials with docetaxel and prednisone (DP) or a DP-containing regimen. Individual participant data from 8820 men with mCRPC randomly assigned on nine phase III trials to receive DP or a DP-containing regimen were combined. Men enrolled in these trials had a diagnosis of prostate adenocarcinoma. The median overall survival was 18.8 months (95% confidence interval [CI] = 17.4 to 22.1 months) and 21.2 months (95% CI = 20.8 to 21.7 months) for Asian and white men, respectively. The pooled hazard ratio for death for Asian men compared with white men, adjusted for baseline prognostic factors, was 0.95 (95% CI = 0.84 to 1.09), indicating that Asian men were not at increased risk of death. This large analysis showed that Asian men did not have shorter OS duration than white men treated with docetaxel.

Identifiers

PMID32368717
PMCPMC7190204
OpenAlexW3003418338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.