Evidence map›Paper›PMID 32368716›Full record

ArticleJNCI cancer spectrum2020

Racial Disparities in Cancer Presentation and Outcomes: The Contribution of Overdiagnosis.

Andrea R Marcadis, Louise Davies, Jennifer L Marti, Luc G T Morris

Open access · goldAbstract read
In one paragraph

Article in JNCI cancer spectrum, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Inequities in Thyroid Cancer Care: Populations Most at Risk for Delays in Diagnosis and Treatment.Thyroid : official journal of the American Thyroid Association · 2023
    Article
  3. COVID-19 in people with neurofibromatosis 1, neurofibromatosis 2, or schwannomatosis.Genetics in medicine : official journal of the American College of Medical Genetics · 2023
    Article
  4. Article
  5. Epidemiology of Thyroid Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  6. Disparities in Thyroid Care.Endocrinology and metabolism clinics of North America · 2022
    Review
  7. Function-related Indicators and Outcomes of Screening Mammography in Older Women: Evidence from the Breast Cancer Surveillance Consortium Cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Andrea R MarcadisHead and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0001-8439-5705
Louise DaviesVA Outcomes Group, Department of Veterans Affairs Medical Center, White River Junction, VT, USA.ORCID 0000-0001-5581-2813
Jennifer L MartiBreast Center, Weill Cornell Medicine, Section of Breast Surgery and Section of Endocrine Surgery, Department of Surgery, New York Presbyterian/Weill Cornell Medical Center, New York, NY, USA.ORCID 0000-0002-0568-4953
Luc G T MorrisHead and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-4417-2280
Memorial Sloan Kettering Cancer Center · USCornell University · USDartmouth Institute for Health Policy and Clinical Practice · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
HEAD AND NECK TRAINING PROGRAM SURGICAL ONCOLOGYT32CA009685 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI FAGIN, JAMES A, WONG, RICHARD J · 1992 to 2022
$3.6M
Identifying and targeting neoantigens in aggressive salivary carcinomasR01DE027738 · NIDCR · SLOAN-KETTERING INST CAN RESEARCH · PI CHAN, TIMOTHY AN-THY, HO, ALAN L. · 2018 to 2022
$2.8M
Functionalizing recurrent FAT1 mutations and deletions in oral cancerK08DE024774 · NIDCR · SLOAN-KETTERING INST CAN RESEARCH · PI MORRIS, LUC GORDON TRANG · 2014 to 2018
$682k
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA023108NCI NIH HHS T32 CA009685NIDCR NIH HHS K08 DE024774NIDCR NIH HHS R01 DE027738
6 · The paper itself

Abstract

backgroundRacial disparities in cancer have been attributed to population differences in access to care. Differences in cancer overdiagnosis rates are another, less commonly considered cause of disparities. Here, we examine the contribution of overdiagnosis to observed racial disparities in papillary thyroid cancer and estrogen/progesterone receptor positive (ER/PR+) breast cancer.

methodsWe used Surveillance, Epidemiology, End-Results (SEER) 13 for analysis of white and black non-Hispanic persons with papillary thyroid cancer or ER/PR+ breast cancer (1992-2014). Analyses were performed using SeerStat (v8.3.5, March 2018). All statistical tests were two-sided.

resultsWhite persons had higher incidence of papillary thyroid cancer than black persons (14.3 vs 7.7 cases per 100 000 age-adjusted population) and ER/PR+ breast cancer (94.8 vs 70.9 cases per 100 000 age-adjusted population) (

conclusionsDifferences in low-risk cancer identification among populations lead to overestimation of racial disparities. Estimates of overdiagnosed cases should be considered to improve care and eliminate disparities while minimizing harms of overdiagnosis.

Identifiers

PMID32368716
PMCPMC7190210
OpenAlexW2999766800

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.