Evidence map›Paper›PMID 32368512›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2020

Akhtar Rasool, Muhammad Zulfajri, Arif Gulzar, Marlia Mohd Hanafiah, Syeda Azeem Unnisa, Mohammed Mahboob

Open access · goldAbstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. COScientific reports · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Akhtar RasoolToxicology Unit, Applied Biology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, Telangana India.
Muhammad ZulfajriDepartment of Chemistry Education, Universitas Serambi Mekkah, Banda Aceh 23245, Aceh, Indonesia.
Arif GulzarKey Laboratory of Material Science and Chemical Engineering, Harbin Engineering University, Heilongjiang 150001, Harbin, China.
Marlia Mohd HanafiahDepartment of Earth Sciences and Environment, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM Bangi 43600, Selangor, Malaysia.
Syeda Azeem UnnisaDepartment of Environmental Sciences, UCS, Osmania University, Hyderabad, 500007, Telangana, India.
Mohammed MahboobToxicology Unit, Applied Biology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, Telangana India.
Osmania University · INHarbin Engineering University · CNIndian Institute of Chemical Technology · INNational University of Malaysia · MYUniversitas Serambi Mekkah · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cobalt nanoparticles (Co-NPs) have been extensively used in clinical practices and medical diagnosis. In this study, the potential toxicity effects of Co-NPs with special emphasis over the biochemical enzyme activities, such as aspartate aminotransferase (ASAT) and alanine aminotransferase (ALAT) in serum, liver, and kidney of Wistar rats were investigated. This toxicity measurement of nanomaterials can support the toxicological data. The biochemical enzymatic variations are powerful tools for the assessment of toxicity. ASAT and ALAT enzymes have been widely used to predict tissue-specific toxicities associated with xenobiotic. The biochemical changes induced by Co-NPs have significance in their toxicological studies because the alterations in biochemical parameters before clinical symptoms indicate either their toxicant safety or detrimental effect. Herein, Co-NPs with particle size <50 nm significantly activated ASAT and ALAT enzymes in the serum, liver, and kidney of rats at concentration-dependent order.

Indexed as

ALATASATBiochemicalCobalt nanoparticlesEnzymeKidneyLiverserumToxicityWistar rats

Identifiers

PMID32368512
PMCPMC7184135
OpenAlexW3018861555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.