ArticleJournal of Cancer2020
Development and Validation of an Individualized Nomogram for Predicting Survival in Patients with Esophageal Carcinoma after Resection.
Article in Journal of Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review and validation of clinical models predicting survival after oesophagectomy for adenocarcinoma.The British journal of surgery · 2022Pooled it
- Y Chromosome Haplogroups and Susceptibility to Esophageal Squamous Cell Carcinoma: An Exploratory Association and Diagnostic Modeling Study.Molecular genetics & genomic medicine · 2026Article
- Biological significance, molecular mechanisms and clinical potential of EI24 in cancer.Chinese medical journal · 2026Review
- A combined tumor burden-based nomogram for synchronous esophageal and gastric cancers: development and external validation.Frontiers in oncology · 2026Article
- Growth factor receptors IGF-1R and VEGFR2 are associated with the prognosis of patients with esophageal cancer after esophagectomy.Open life sciences · 2026Article
- Nomograms for prognosis prediction in esophageal adenocarcinoma: realities and challenges.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Review
- Nomogram model for predicting long-term survival in esophageal cancer patients with metastasis after treatment: a SEER-based study.Journal of thoracic disease · 2024Article
- Development and validation of a prognostic nomogram for esophageal cancer patients based on SEER Asian population.Scientific reports · 2024Article
- The percentages of signet-ring cells (SRCs) affects the prognosis after radical gastrectomy for advanced gastric cancer.Langenbeck's archives of surgery · 2023Article
- A novel staging system based on deep learning for overall survival in patients with esophageal squamous cell carcinoma.Journal of cancer research and clinical oncology · 2023Article
- Article
- Patterns of care and prognostic evaluation for stage I-III upper esophageal squamous cell carcinoma: a population-based study.Annals of translational medicine · 2022Article
- [Development and validation of a prognostic model based on SEER data for patients with esophageal carcinoma after esophagectomy].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Article
- Increased prognostic value of clinical-reproductive model in Chinese female patients with esophageal squamous cell carcinoma.World journal of gastroenterology · 2022Article
- Real-world experience with anti-programmed cell death protein 1 immunotherapy in patients with esophageal cancer: A retrospective single-center study.Frontiers in oncology · 2022Article
- Pyroptosis impacts the prognosis and treatment response in gastric cancer via immune system modulation.American journal of cancer research · 2022Article
- The Evaluation of a SEER-Based Nomogram in Predicting the Survival of Patients Treated with Neoadjuvant Therapy Followed by Esophagectomy.Frontiers in surgery · 2022Article
- Article
- Narrative review of pembrolizumab for the treatment of esophageal cancer: evidence and outlook.Annals of translational medicine · 2021Review
- Prognostic biomarkers and therapeutic targets in oral squamous cell carcinoma: a study based on cross-database analysis.Hereditas · 2021Article
Corrections and comments
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
An accurate estimation of prognosis of the esophageal carcinoma patients after surgery is urgently needed. Clinical nomogram has been developed to quantify risk by incorporating prognostic factors for individual patient. Based on the Surveillance, Epidemiology, and End Results (SEER) database from 2004 to 2013, a total of 4566 patients were selected. Of those, 3198 patients were assigned to training set to construct the nomogram, which incorporated age, gender, histology, grade, T stage, N stage, nodes examined, radiation and chemotherapy. The calibration curve for probability of survival showed good agreement between prediction by nomogram and actual observation. The C-index of the nomogram was 0.71(95%CI 0.70-0.72), which was statistically higher than the TNM staging system. The results were then validated using bootstrap resampling and a validation set of 1368 patients in the SEER database. Besides, in the esophageal squamous cell carcinoma and esophageal adenocarcinoma subgroups, the nomogram discrimination was superior to the TNM staging system. It is likely that these results would play a supplementary role in the current staging system and help to identify the high risk population after surgery.
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