Evidence map›Paper›PMID 32368241›Full record

ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2020

Long-term effect of anticoagulation following left atrial appendage occlusion with the LARIAT device in patients with nonvalvular atrial fibrillation: impact on thromboembolism, bleeding and mortality. Real life data.

Radosław Litwinowicz, Grzegorz Filip, Dorota Sobczyk, Dhanunjaya Lakkireddy, Venkat L K Vuddanda, Magdalena Bartuś, Bogusław Kapelak, Krzysztof Bartuś

Open access · goldAbstract read
In one paragraph

Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. A decade later: long-term results of the first percutaneous epicardial closure of the left atrial appendage using the LARIAT device.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2023
    Article
  3. Review
  4. Article
  5. Article
  6. Adverse outcomes in anticoagulated patients undergoing percutaneous left atrial appendage ligation.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Radosław LitwinowiczDepartment of Cardiovascular Surgery and Transplantology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Grzegorz FilipDepartment of Cardiovascular Surgery and Transplantology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Dorota SobczykEmergency and Admission Department, John Paul II Hospital, Krakow, Poland.
Dhanunjaya LakkireddyThe Kansas City Heart Rhythm Institute, Overland Park Regional Hospital, University of Kansas, Kansas, USA.
Venkat L K VuddandaBrigham and Women's Hospital, Harvard Medical School, Boston MA, USA.
Magdalena BartuśDepartment of Pharmacology, Jagiellonian University Medical College, Krakow, Poland.
Bogusław KapelakDepartment of Cardiovascular Surgery and Transplantology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Krzysztof BartuśDepartment of Cardiovascular Surgery and Transplantology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Jagiellonian University · PLHarvard University · USInstitute of Cardiology · PLJohn Paul II Hospital · PLUniversity of Kansas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIndications for left atrial appendage occlusion (LAAO) are varied and patients require individual management strategies. However, currently no guidelines exist for postprocedure oral anticoagulation (OAC) after an LAAO procedure.

aimTo evaluate the effect of OAC on thromboembolism, bleeding and mortality following the LAAO procedure for patients with AF. MATERIAL AND

methodsOne hundred and thirty-nine consecutive patients with nonvalvular atrial fibrillation (NVAF) who underwent LAAO with the LARIAT device were followed for at least 40 months. Decisions about OAC and its modifications were individualized based on clinical presentation, patient and physician preferences.

resultsFollowing LAAO, 52 (41%) patients did not receive OAC (No-OAC group) and 75 (59%) patients received OAC (OAC group), without any intergroup differences in CHADS

conclusionsThere is no need for OAC after the LAAO procedure. Omitting OAC after an LAAO procedure in AF patients: (1) has similar stroke prevention rates as patients on OAC, (2) has similar bleeding prevention rates as patients on OAC, (3) has similar safety endpoints and long-term efficacy as patients on OAC.

Indexed as

anticoagulant treatmentatrial fibrillationleft atrial appendageleft atrial appendage occlusionstroke

Identifiers

PMID32368241
PMCPMC7189129
OpenAlexW3018952863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.