Evidence map›Paper›PMID 32368197›Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2020

Bayesian network analysis of plasma microRNA sequencing data in patients with venous thrombosis.

Florian Thibord, Gaëlle Munsch, Claire Perret, Pierre Suchon, Maguelonne Roux, Manal Ibrahim-Kosta, Louisa Goumidi, Jean-François Deleuze, Pierre-Emmanuel Morange, David-Alexandre Trégouët

Open access · bronzeAbstract read
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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  8. Thrombosis: Grand Challenges Ahead!Frontiers in cardiovascular medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Florian ThibordInstitut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1219, Bordeaux Population Health Research Center, University of Bordeaux, 146 rue Léo Saignat, Bordeaux 33076, France.
Gaëlle MunschInstitut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1219, Bordeaux Population Health Research Center, University of Bordeaux, 146 rue Léo Saignat, Bordeaux 33076, France.
Claire PerretSorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), INSERM UMR_S 1166, 91 Boulevard de l'Hôpital, Paris 75013, France.
Pierre SuchonLaboratory of Haematology, La Timone Hospital, 278 rue Saint Pierre, Marseille 13385, France.
Maguelonne RouxSorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), INSERM UMR_S 1166, 91 Boulevard de l'Hôpital, Paris 75013, France.
Manal Ibrahim-KostaLaboratory of Haematology, La Timone Hospital, 278 rue Saint Pierre, Marseille 13385, France.
Louisa GoumidiINSERM UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Center for CardioVascular and Nutrition research (C2VN), Aix-Marseille University, 278 rue Saint Pierre, Marseille 13385, France.
Jean-François DeleuzeCentre National de Recherche en Génomique Humaine, Direction de la Recherche Fondamentale, CEA, 2 rue Gaston Crémieux, Evry 91057, France.
Pierre-Emmanuel MorangeLaboratory of Haematology, La Timone Hospital, 278 rue Saint Pierre, Marseille 13385, France.
David-Alexandre TrégouëtInstitut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1219, Bordeaux Population Health Research Center, University of Bordeaux, 146 rue Léo Saignat, Bordeaux 33076, France.
Inserm · FRHôpital de la Timone · FRUniversité de Bordeaux · FRCentre National de Recherche en Génomique Humaine · FRNutrition, Obésité et Risque Thrombotique · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small regulatory RNAs participating to several biological processes and known to be involved in various pathologies. Measurable in body fluids, miRNAs have been proposed to serve as efficient biomarkers for diseases and/or associated traits. Here, we performed a next-generation-sequencing based profiling of plasma miRNAs in 344 patients with venous thrombosis (VT) and assessed the association of plasma miRNA levels with several haemostatic traits and the risk of VT recurrence. Among the most significant findings, we detected an association between hsa-miR-199b-3p and haematocrit levels (

Indexed as

BiomarcadoresBiomarkersEstudio de asociaciónGenoma completoGenome Wide Association StudyNext generation sequencingplasma miRNAPlasma miRNASecuenciación de última generaciónTrombosis venosaVenous thrombosis

Identifiers

PMID32368197
PMCPMC7189740
OpenAlexW3021092810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.