Evidence map›Paper›PMID 32368113›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020

Common and Unique Factors and the Bidirectional Relationship Between Chronic Kidney Disease and Nonalcoholic Fatty Liver in Type 2 Diabetes Patients.

Yau-Jiunn Lee, Chao-Ping Wang, Wei-Chin Hung, Wei-Hua Tang, Yu-Hung Chang, Der-Wei Hu, Yung-Chuan Lu, Teng-Hung Yu, Cheng-Ching Wu, Fu-Mei Chung and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yau-Jiunn LeeLee's Endocrinology Clinic, Pingtung 90000, Taiwan.
Chao-Ping WangDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan.
Wei-Chin HungDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan.
Wei-Hua TangLee's Endocrinology Clinic, Pingtung 90000, Taiwan.
Yu-Hung ChangLee's Endocrinology Clinic, Pingtung 90000, Taiwan.ORCID 0000-0001-6116-1893
Der-Wei HuLee's Endocrinology Clinic, Pingtung 90000, Taiwan.
Yung-Chuan LuSchool of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung 82445, Taiwan.
Teng-Hung YuDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan.
Cheng-Ching WuDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan.
Fu-Mei ChungDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan.
Chia-Chang HsuThe School of Chinese Medicine for Post Baccalaureate, College of Medicine, I-Shou University, Kaohsiung 82445, Taiwan.ORCID 0000-0001-6620-8013
E-Da Hospital · TWPingtung Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate the common and unique risk factors and bidirectional relationship between chronic kidney disease (CKD) and nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM). PATIENTS AND

methodsThis was a cross-sectional study of patients with T2DM enrolled in a disease management program at two specialized diabetes outpatient clinics. Common and unique risk factors for CKD and NAFLD were examined using structural equation models (SEMs). SEMs were also used to examine direct and indirect effects of NAFLD on CKD and those of CKD on NAFLD.

resultsA total of 1992 subjects with T2DM were enrolled in this study. In multivariate analysis, NAFLD was independently associated with the odds of CKD (adjusted odds ratio=1.59, 95% confidence interval=1.12-2.25,

conclusionCommon and unique risk factors and a bidirectional relationship existed between CKD and NAFLD in our patients with T2DM.

Indexed as

bidirectional relationshipchronic kidney diseasenonalcoholic fatty liver diseaserisk factorstructural equation modelingtype 2 diabetes mellitus

Identifiers

PMID32368113
PMCPMC7173841
OpenAlexW3016742628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.