Evidence map›Paper›PMID 32368042›Full record

ArticleInternational journal of nanomedicine2020

Synthesis, Characterization, Biomedical Application, Molecular Dynamic Simulation and Molecular Docking of Schiff Base Complex of Cu(II) Supported on Fe

Rahime Eshaghi Malekshah, Bahareh Fahimirad, Ali Khaleghian

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. FeScientific reports · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rahime Eshaghi MalekshahDepartment of Chemistry, College of Science, Semnan University, Semnan, Iran.
Bahareh FahimiradDepartment of Chemistry, College of Science, Semnan University, Semnan, Iran.
Ali KhaleghianBiochemistry Department, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOver the past several years, nano-based therapeutics were an effective cancer drug candidate in order to overcome the persistence of deadliest diseases and prevalence of multiple drug resistance (MDR).

methodsThe main objective of our program was to design organosilane-modified Fe

resultsThe results showed that the anti-cancer activity was barely reduced after modifying the surface of the Fe

conclusionResults of biology activities and computational modeling demonstrate that nanoparticles were targeted drug delivery system in cancer treatment.

Indexed as

Molecular Docking SimulationMolecular Dynamics SimulationApoptosisCell NucleusCopperDNADNA Topoisomerases, Type IIFerric CompoundsHumansK562 CellsMagneticsMagnetite NanoparticlesPropylaminesSchiff BasesSilanesSilicon Dioxideamino-propyl-triethoxysilaneCopperDNADNA Topoisomerases, Type IIFerric Compoundsferric oxideMagnetite NanoparticlesPropylaminesSchiff BasesSilanesSilicon Dioxideapoptosiscomputational methodscore–shellmolecular dockingMTT assaySchiff basesuperparamagneticTopoisomerase II

Identifiers

PMID32368042
PMCPMC7182715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.