Evidence map›Paper›PMID 32368033›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2020

Patient Selection for Bronchoscopic Lung Volume Reduction.

Jorrit B A Welling, Jorine E Hartman, Sonja W S Augustijn, Huib A M Kerstjens, Lowie E G W Vanfleteren, Karin Klooster, Dirk-Jan Slebos

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Review
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  4. Observational
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Lung volume reduction: surgeryBreathe (Sheffield, England) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Crosslink bio-adhesives for bronchoscopic lung volume reduction: current status and future direction.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jorrit B A WellingUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, the Netherlands.ORCID 0000-0001-6754-4668
Jorine E HartmanUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, the Netherlands.ORCID 0000-0001-8765-9673
Sonja W S AugustijnUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, the Netherlands.
Huib A M KerstjensUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, the Netherlands.ORCID 0000-0001-7705-7927
Lowie E G W VanfleterenCOPD Center, Sahlgrenska University Medical Hospital and Institute of Medicine, Gothenburg University, Gothenburg, Sweden.
Karin KloosterUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, the Netherlands.
Dirk-Jan SlebosUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, the Netherlands.
University Medical Center Groningen · NLSahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Bronchoscopic lung volume reduction (BLVR) is a valuable treatment option for carefully selected patients with severe COPD. There is limited knowledge about the characteristics and outcomes of patients referred to a specialized center for BLVR. The study objectives were to investigate the selection rate for BLVR treatment in patients referred for this treatment and to investigate the differences between patients that were selected for BLVR and patients that were not. Patients and Methods: We performed a retrospective analysis of patients with severe COPD who were referred to our hospital to assess eligibility for BLVR treatment. Our parameters included demographics, comorbidity, chest computed tomography characteristics, reasons for rejection from BLVR treatment and patient survival. Results: In total, 1500 patients were included (mean age 62 years, 50% female and forced expiratory volume in 1 s 33% of predicted). Out of this group, 282 (19%) patients were selected for BLVR treatment. The absence of a suitable target lobe for treatment, an unsuitable disease phenotype and insufficient lung hyperinflation were the most important factors for not being selected. Patients that were selected for any BLVR option lived significantly longer than the group of patients that were not selected for BLVR (median 3060 versus 2079 days, P<0.001). Conclusion: We found that only a small proportion of patients that are referred for BLVR treatment is eligible for a BLVR treatment, indicating a need for both better referral tools and for the development of new therapies for this group of patients. Furthermore, our data suggest that selection for BLVR is associated with a significant survival benefit.

Indexed as

Patient SelectionPneumonectomyPulmonary Disease, Chronic ObstructivePulmonary EmphysemaBronchoscopyFemaleHumansMaleMiddle AgedRetrospective Studiesbronchoscopic lung volume reductionendobronchial valveslung volume reduction coilspatient selection

Identifiers

PMID32368033
PMCPMC7185646
OpenAlexW3018466624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.