Evidence map›Paper›PMID 32367800›Full record

ArticleeLife2020

Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes.

Laura E Kuil, Nynke Oosterhof, Giuliano Ferrero, Tereza Mikulášová, Martina Hason, Jordy Dekker, Mireia Rovira, Herma C van der Linde, Paulina Mh van Strien, Emma de Pater and 4 more

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Laura E KuilDepartment of Clinical Genetics, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID 0000-0003-3330-1371
Nynke Oosterhof *Department of Clinical Genetics, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Giuliano Ferrero *Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Tereza MikulášováLaboratory of Cell Differentiation, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Martina HasonLaboratory of Cell Differentiation, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Jordy DekkerDepartment of Clinical Genetics, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Mireia RoviraInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Herma C van der LindeDepartment of Clinical Genetics, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Paulina Mh van StrienDepartment of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands.
Emma de PaterDepartment of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands.
Gerben SchaafDepartment of Clinical Genetics, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID 0000-0003-0189-9073
Erik Mj BindelsDepartment of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands.
Valerie Wittamer *Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID 0000-0003-0003-2646
Tjakko J van Ham *Department of Clinical Genetics, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID 0000-0002-2175-8713
Erasmus MC · NLUniversité Libre de Bruxelles · BECzech Academy of Sciences, Institute of Molecular Genetics · CZ

Funding

Czech Science Foundation 18-18363SErasmus University Rotterdam University FellowshipFonds De La Recherche Scientifique - FNRS F451218FFonds de la Recherche Scientifique FNRS under Incentive Grant for Scientific Research F451218FMarie Curie 322368Marie Curie Career Integration Grant 322368WELBIO WELBIO-CR-2015S-04ZonMw VENI 016.136.150
6 · The paper itself

Abstract

Macrophages derive from multiple sources of hematopoietic progenitors. Most macrophages require colony-stimulating factor 1 receptor (CSF1R), but some macrophages persist in the absence of CSF1R. Here, we analyzed

Indexed as

AnimalsCell ProliferationGene Expression ProfilingMacrophagesMicrogliaProtein-Tyrosine KinasesReceptor, Macrophage Colony-Stimulating FactorReceptor Protein-Tyrosine KinasesReceptors, Granulocyte-Macrophage Colony-Stimulating FactorZebrafishZebrafish Proteinscsf1ra protein, zebrafishProtein-Tyrosine KinasesReceptor, Macrophage Colony-Stimulating FactorReceptor Protein-Tyrosine KinasesReceptors, Granulocyte-Macrophage Colony-Stimulating FactorZebrafish ProteinsCSF1Rdevelopmental biologyhematopoiesislangerhans cellsmacrophagesmetaphocytesmicrogliazebrafish

Identifiers

PMID32367800
PMCPMC7237208
OpenAlexW3021971824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.