Evidence map›Paper›PMID 32367189›Full record

Trial reportThe international journal of cardiovascular imaging2020

Cardiac cine CT approaching 1 mSv: implementation and assessment of a 58-ms temporal resolution protocol.

Younhee J Choi, Mark A Ahlman, Marissa Mallek, Tyler E Cork, Marcus Y Chen, David A Bluemke, Veit Sandfort

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in The international journal of cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Younhee J ChoiDepartment of Radiology and Imaging Sciences, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA.
Mark A AhlmanDepartment of Radiology and Imaging Sciences, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA.
Marissa MallekDepartment of Radiology and Imaging Sciences, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA.
Tyler E CorkDepartment of Radiology and Imaging Sciences, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA.
Marcus Y ChenAdvanced Cardiovascular Imaging Laboratory, National Heart, Lung, and Blood Institute, 10 Center Drive, Bethesda, MD, 20892, USA.
David A BluemkeDepartment of Radiology and Imaging Sciences, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA.
Veit SandfortDepartment of Radiology and Imaging Sciences, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA. veit.sandfort@googlemail.com.ORCID http://orcid.org/0000-0001-7218-9306
National Institutes of Health · USNational Heart Lung and Blood Institute · US

Funding

Cardiovascular CT Clinical ResearchZIAHL006220 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHEN, MARCUS · 2017 to 2025
$22.5M
6 · The paper itself

Abstract

Clinical use of cardiac cine CT imaging is limited by high radiation dose and low temporal resolution. To evaluate a low radiation dose, high temporal resolution cardiac cine CT protocol in human cardiac CT and phantom scans. CT scans of a circulating iodine target were reconstructed using the conventional single heartbeat half-scan (HS, approx. 175 ms temporal resolution) and the 3-heartbeat multi-segment (MS, approx. 58 ms) algorithms. Motion artifacts were quantified by the root-mean-square error (RMSE). Low-dose cardiac cine CT scans were performed in 55 subjects at a tube potential of 80 kVp and current of 80 mA. Image quality of HS and MS scans was assessed by blinded reader quality assessment, left ventricular (LV) free wall motion, and LV ejection rate. Motion artifacts in phantom scans were higher in HS than in MS reconstructions (RSME 188 and 117 HU, respectively; p = 0.001). Median radiation dose in human scans was 1.2 mSv. LV late diastolic filling was observed more frequently in MS than in HS images (42 vs. 26 subjects, respectively; p < 0.001). LV free wall systolic motion was more physiologic and had less error in MS than in HS reconstructions (sum-of-squared errors 34 vs. 45 mm

Indexed as

Radiographic Image Interpretation, Computer-AssistedStroke VolumeTomography, X-Ray ComputedVentricular Function, LeftAgedArtifactsFeasibility StudiesFemaleHeartHeart RateHumansMaleMiddle AgedPhantoms, ImagingPredictive Value of TestsProspective StudiesCardiac cine CTRadiation doseReconstruction methodsTemporal resolution

Identifiers

PMID32367189
OpenAlexW3021414169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.