Evidence map›Paper›PMID 32367053›Full record

ArticleNature microbiology2020

Fetal inheritance of chromosomally integrated human herpesvirus 6 predisposes the mother to pre-eclampsia.

Francesca Gaccioli, Susanne Lager, Marcus C de Goffau, Ulla Sovio, Justyna Dopierala, Sungsam Gong, Emma Cook, Andrew Sharkey, Ashley Moffett, Wai Kwong Lee and 7 more

Open access · greenAbstract readLetter
In one paragraph

Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Endogenous human herpesviruses 6A/B.Journal of virology · 2025
    Article
  8. Article
  9. Enterovirus Placentitis is an Underrecognized Cause of Placental Pathology.The American journal of surgical pathology · 2025
    Article
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Francesca Gaccioli *Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.
Susanne Lager *Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-3556-065X
Marcus C de Goffau *Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Ulla SovioDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-0799-1105
Justyna DopieralaDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.
Sungsam GongDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5796-4423
Emma CookDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-6142-4443
Andrew SharkeyCentre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Ashley MoffettCentre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Wai Kwong LeeInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Christian DellesInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0003-2238-2612
Cristina VenturiniDivision of Infection and Immunity, University College London, London, UK.
Judith BreuerDivision of Infection and Immunity, University College London, London, UK.ORCID http://orcid.org/0000-0001-8246-0534
Julian ParkhillDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-7069-5958
Sharon J PeacockDepartment of Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-1718-2782
D Stephen Charnock-JonesDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-2936-4890
Gordon C S SmithDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK. gcss2@cam.ac.uk.ORCID http://orcid.org/0000-0003-2124-0997
University of Cambridge · GBUniversity of Glasgow · GBGreat Ormond Street Hospital for Children NHS Foundation Trust · GBUniversity College London · GBUppsala University · SE

Funding

Department of HealthMedical Research Council G1100221Medical Research Council MR/K021133/1Medical Research Council MR/P001092/1Wellcome Trust
6 · The paper itself

Abstract

Pre-eclampsia (typically characterized by new-onset hypertension and proteinuria in the second half of pregnancy) represents a major determinant of the global burden of disease

Indexed as

Disease SusceptibilityMaternal InheritanceVirus IntegrationCase-Control StudiesDNA, ViralFemaleHerpesvirus 6, HumanHumansInfantInfant, NewbornMalePolymorphism, Single NucleotidePre-EclampsiaPregnancyRNA, ViralRoseolovirus InfectionsDNA, ViralRNA, Viral

Identifiers

PMID32367053
PMCPMC7610361
OpenAlexW3023192880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.