ArticleNature ecology & evolution2020
The influence of feeding behaviour and temperature on the capacity of mosquitoes to transmit malaria.
Article in Nature ecology & evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 53 citations in OpenAlex.
- Climatic drivers of the 2024 malaria outbreak in two neighbouring districts in northeastern India and its corridor: The indirect role of El Niño.One health (Amsterdam, Netherlands) · 2026Article
- Disentangling Environmental and Within-Host Drivers of Parasite Dynamics in Natural Populations.Molecular ecology · 2026Article
- Associations between weather and Plasmodium vivax malaria in an Amazonian elimination setting: a distributed lag analysis from 2017 to 2024.Malaria journal · 2026Article
- Zoonotic malaria in Southeast Asia's changing landscapes: vector complexity, challenges, and future strategies.Parasites & vectors · 2026Review
- Assessing the impact of climate and control interventions on spatio-temporal malaria dynamics using a stochastic metapopulation model.PLoS computational biology · 2026Article
- Article
- Stage-dependent trade-offs in thermal performance: fluctuating temperatures reverse larval and adult fitness in Anopheles gambiae and An. coluzzii.Journal of medical entomology · 2026Article
- Environmental Factors That Regulate Mosquito Physiology and Behavior.Annual review of entomology · 2026Review
- Anthropogenic landscapes and vector-borne disease dynamics: Unveiling the complex interplay between Human Footprint and disease transmission in Colombia.PLOS global public health · 2026Article
- Phenotypic variation in populations of the mosquito vector, Aedes aegypti, and implications for predicting the effects of temperature and climate change on dengue transmission.PLoS neglected tropical diseases · 2025Article
- Evaluation of the efficacy of 20% IR3535Parasites & vectors · 2025Article
- Biting time of day in malaria mosquitoes is modulated by nutritional status.Malaria journal · 2025Article
- Biting time of day in malaria mosquitoes is modulated by nutritional status.bioRxiv : the preprint server for biology · 2025Article
- Fluctuating Warm and Humid Conditions Differentially Impact Immunity and Development in the Malaria Vector Anopheles stephensi.Global change biology · 2025Article
- Mean daily temperatures predict the thermal limits of malaria transmission better than hourly rate summation.Nature communications · 2025Article
- Modelling the effects of diurnal temperature variation on malaria infection dynamics in mosquitoes.Communications biology · 2025Article
- Regulation of diel locomotor activity and retinal responses of Anopheles stephensi by ingested histamine and serotonin is temperature- and infection-dependent.PLoS pathogens · 2025Article
- Impact of temperatures on malaria incidence in vulnerable regions of Pakistan: empirical evidence and future projections.Epidemiology and infection · 2025Article
- Simplified Plasmodium falciparum membrane feeding assay using small Petri dishes and gel warmers.Malaria journal · 2024Article
- Associations between weather andmedRxiv : the preprint server for health sciences · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Insecticide-treated bed nets reduce malaria transmission by limiting contact between mosquito vectors and human hosts when mosquitoes feed during the night. However, malaria vectors can also feed in the early evening and in the morning when people are not protected. Here, we explored how the timing of blood feeding interacts with environmental temperature to influence the capacity of Anopheles mosquitoes to transmit the human malaria parasite Plasmodium falciparum. In laboratory experiments, we found no effect of biting time itself on the proportion of mosquitoes that became infectious (vector competence) at constant temperature. However, when mosquitoes were maintained under more realistic fluctuating temperatures, there was a significant increase in competence for mosquitoes feeding in the evening (18:00), and a significant reduction in competence for those feeding in the morning (06:00), relative to those feeding at midnight (00:00). These effects appear to be due to thermal sensitivity of malaria parasites during the initial stages of parasite development within the mosquito, and the fact that mosquitoes feeding in the evening experience cooling temperatures during the night, whereas mosquitoes feeding in the morning quickly experience warming temperatures that are inhibitory to parasite establishment. A transmission dynamics model illustrates that such differences in competence could have important implications for malaria prevalence, the extent of transmission that persists in the presence of bed nets, and the epidemiological impact of behavioural resistance. These results indicate that the interaction of temperature and feeding behaviour could be a major ecological determinant of the vectorial capacity of malaria mosquitoes.
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