Evidence map›Paper›PMID 32366907›Full record

ArticleOncogene2020

YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation.

Chuanzhao Zhang, Shanzhou Huang, Hongkai Zhuang, Shiye Ruan, Zixuan Zhou, Kaijun Huang, Fei Ji, Zuyi Ma, Baohua Hou, Xiaoshun He

Abstract read
PubMed Publisher
In one paragraph

Article in Oncogene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 257 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
257citing papers in PubMed, 1 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

257 citing papers in PubMed, 1 synthesis or guideline pooled it, 430 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. NNature reviews. Cancer · 2026
    Review
  8. Review
  9. Review
  10. mFrontiers in cell and developmental biology · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. mActa pharmaceutica Sinica. B · 2025
    Review
  18. [circ_EPHB4 synergizes with YTHDF3 to promote glioma progressionNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  19. Hypoxia-mediated mJournal of translational medicine · 2025
    Review
  20. Article

197 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chuanzhao Zhang *Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China. 641703837@qq.com.ORCID http://orcid.org/0000-0001-6553-4458
Shanzhou Huang *Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Hongkai ZhuangDepartment of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Shiye RuanDepartment of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Zixuan ZhouDepartment of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Kaijun HuangDepartment of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Fei JiDepartment of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Zuyi MaDepartment of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Baohua HouDepartment of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, 510080, China. 15917919681@163.com.
Xiaoshun HeOrgan Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China. 13922171191@163.com.
Guangdong Academy of Medical Sciences · CNGuangdong General Hospital · CNShantou University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N

Indexed as

AdenosineAnimalsCarcinoma, HepatocellularGene Expression Regulation, NeoplasticHep G2 CellsHumansLiverLiver NeoplasmsMaleMethylationMiceMice, Inbred BALB CMice, NudeNeoplasm MetastasisNeoplasm TransplantationNeoplastic Stem CellsAdenosineN-methyladenosineOctamer Transcription Factor-3POU5F1 protein, humanRNA-Binding ProteinsRNA, MessengerYTHDF2 protein, human

Identifiers

PMID32366907
OpenAlexW3022834896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.