Evidence map›Paper›PMID 32366715›Full record

ArticleAntimicrobial agents and chemotherapy2020

Optimal Dose or Optimal Exposure? Consideration for Linezolid in Tuberculosis Treatment.

Hannah Yejin Kim, Shashikant Srivastava, Hemanth Kumar Ak, Ben J Marais, Jan-Willem Alffenaar

Abstract readLetterComment
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Hannah Yejin KimSydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Camperdown, Australia hannah.kim@sydney.edu.au.ORCID 0000-0002-1808-5036
Shashikant SrivastavaTexas Tech University Health Science Center, School of Pharmacy, Division of Clinical and Translational Research, Dallas, Texas, USA.
Hemanth Kumar AkNational Institute for Research in Tuberculosis, Chennai, India.
Ben J MaraisMarie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Camperdown, Australia.
Jan-Willem AlffenaarSydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Camperdown, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Tuberculosis, Multidrug-ResistantTuberculosis, PulmonaryAdultHumansLinezolidLinezoliddrug exposurelinezolidpharmacokineticsPK/PDprecision dosingTDMtuberculosis

Identifiers

PMID32366715
PMCPMC7318018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.