Evidence map›Paper›PMID 32366357›Full record

ArticleeLife2020

mRNA decapping is an evolutionarily conserved modulator of neuroendocrine signaling that controls development and ageing.

Fivos Borbolis, John Rallis, George Kanatouris, Nikolitsa Kokla, Antonis Karamalegkos, Christina Vasileiou, Katerina M Vakaloglou, George Diallinas, Dimitrios J Stravopodis, Christos G Zervas and 1 more

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Genome-wide mapping of DCP2-dependent 5' cap footprints inNAR genomics and bioinformatics · 2026
    Article
  2. Article
  3. PLAA/UFD-3 regulates P-bodies through its intrinsic disordered domain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Fivos BorbolisBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.ORCID 0000-0001-6559-1356
John RallisBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.
George KanatourisBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.
Nikolitsa KoklaBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.
Antonis KaramalegkosBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.
Christina VasileiouBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.
Katerina M VakaloglouBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.
George DiallinasDepartment of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-3426-726X
Dimitrios J StravopodisDepartment of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.
Christos G ZervasBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.ORCID 0000-0003-0531-9515
Popi SyntichakiBiomedical Research Foundation of the Academy of Athens, Center of Basic Research, Athens, Greece.ORCID 0000-0001-9536-8905
National and Kapodistrian University of Athens · GRBiomedical Research Foundation of the Academy of Athens · GRDemocritus University of Thrace · GR

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
European Research Council 201975NIH HHS P40 OD010440NIH HHS P40 OD018537
6 · The paper itself

Abstract

Eukaryotic 5'-3' mRNA decay plays important roles during development and in response to stress, regulating gene expression post-transcriptionally. In

Indexed as

AgingAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDrosophila melanogasterDrosophila ProteinsEndoribonucleasesForkhead Transcription FactorsGene Expression Regulation, DevelopmentalNeuronsNeurosecretory SystemsRNA, MessengerRNA StabilityCaenorhabditis elegans Proteinsdaf-16 protein, C elegansDCAP-1 protein, C elegansDrosophila ProteinsEndoribonucleasesForkhead Transcription FactorsFOXO protein, DrosophilaRNA, MessengerCaenorhabditis elegansC. elegansDCAP-1/DCP1D. melanogasterDrosophila melanogastergeneticsgenomicsins-7iongevitywing development

Identifiers

PMID32366357
PMCPMC7200159
OpenAlexW3021931547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.