ArticleArthritis research & therapy2020
IgG4-related aortitis/periaortitis and periarteritis: a distinct spectrum of IgG4-related disease.
Article in Arthritis research & therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 64 citations in OpenAlex.
- Sudden cardiac death revealing extensive cardiovascular IgG4-related disease: a forensic autopsy case report.Forensic science, medicine, and pathology · 2026Article
- Inflammatory Aortopathies in Rheumatic Diseases: A State-of-the-Art Review.Diagnostics (Basel, Switzerland) · 2026Review
- Aortitis as a High-Risk Vascular Syndrome: Integrating Phenotype-Driven Diagnosis, Multidisciplinary Assessment, and Personalised Management.Journal of personalized medicine · 2026Review
- Article
- Necrotizing pancreatitis with multifocal hepatic artery pseudoaneurysms: Diagnostic limitations and rare appearance of suspected IgG-4 related disease.Radiology case reports · 2026Article
- IgG4-Related Kidney Disease and IgG4-Related Retroperitoneal Fibrosis: An Update on Diagnosis and Treatment.Kidney international reports · 2026Review
- Management of IgG4-Related Disease.Current rheumatology reports · 2026Review
- IgG4-Related Aortitis Masking as Intramural Hematoma on Imaging.JACC. Case reports · 2026Article
- IgG4-related aortitis mimicking acute aortic and coronary syndromes, multimodality imaging-pathology correlation: a case report.Frontiers in cardiovascular medicine · 2026Article
- Advances in the pathophysiology, diagnosis and treatment of Takayasu arteritis.Nature reviews. Rheumatology · 2025Review
- New Developments in the Treatment of IgG4-Related Disease: A Comprehensive Clinical Approach.Journal of clinical medicine · 2025Review
- Endovascular Treatment for Aortic Diseases: Intercontinental Disparities.Current cardiology reports · 2025Review
- Global research trends and emerging focus areas in IgG4-related disease: a bibliometric and visual analysis.Hereditas · 2025Article
- Unraveling the complexity of IgG4-related aortitis and periarteritis: from pathogenesis to clinical practice.Frontiers in immunology · 2025Review
- Common Femoral Artery Aneurysm: A Rare Manifestation of Immunoglobulin G4-Related Disease.Annals of vascular diseases · 2025Article
- Coronary periarteritis and pericarditis are rare but distinct manifestations of heart involvement in IgG4-related disease: a retrospective cohort study.Orphanet journal of rare diseases · 2024Article
- IgG4-related disease: an update on pathology and diagnostic criteria with a focus on salivary gland manifestations.Virchows Archiv : an international journal of pathology · 2024Review
- Current and future advances in practice: IgG4-related disease.Rheumatology advances in practice · 2024Review
- IgG4-related disease involving coronary and pulmonary arteries: a case report and literature review.Cardiovascular diagnosis and therapy · 2023Article
- Article
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLarge vessels could be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to clarify the clinical features and evaluate the treatment efficacy for IgG4-RD with aortitis/periaortitis and periarteritis (PAO/PA).
methodsThis study prospectively enrolled 587 patients with IgG4-RD with a follow-up time of more than 6 months. The distribution of IgG4-related PAO/PA was classified into four types: type 1, thoracic aorta; type 2a, abdominal aorta; type 2b, abdominal aorta and iliac artery; type 2c, iliac artery; type 3, thoracic and abdominal aorta; and type 4, other arteries. Patient's demographic data, clinical characteristics, laboratory parameters, and treatment efficacy were analyzed.
resultsOf 587 IgG4-RD patients, 89 (15.2%) had PAO/PA. The average age was 58.3 ± 11.1 years, with male predominance (85.4%). Vessels affected were as follows: abdominal aorta (83.1%), iliac artery (70.8%), thoracic aorta (13.5%), and other vessels (13.5%). The most prevalent distribution type of IgG4-related PAO/PA was type 2b, with 74 (83.1%) patients, followed by type 2a, type 2c, type 3, and type 1. Fifty-five (61.8%) PAO/PA patients had hydronephrosis, with renal insufficiency occurring in 43 (48.3%), and 31 (34.8%) PAO/PA patients had D-J stent drainage due to severe ureteral obstruction. After treatment with a glucocorticoid and immunosuppressants, 82% patients achieved remission with shrinking of the perivascular mass by more than 30%.
conclusionsIgG4-RD with PAO/PA was distinct from non-PAO/PA in demographic features, organ involvement distribution, inflammatory markers, and serum IgG4 and IgE. The most common affected vessel was the abdominal aorta, and most patients responded well with treatment.
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