ReviewGenes2020
Sustentacular Cell Enwrapment of Olfactory Receptor Neuronal Dendrites: An Update.
Review in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
46 citing papers in PubMed, 74 citations in OpenAlex.
- Article
- Cell-type Plasticity Supports Behavioral Adaptations at the Water-to-Land Interface.bioRxiv : the preprint server for biology · 2026Article
- Olfactory epithelium regeneration and homeostasis: cellular and molecular mechanisms and novel methodological advances.Cell regeneration (London, England) · 2026Review
- Expression atlas of Dmrt genes across sex and development in the mouse brain: functional insights from the olfactory system.Biology of sex differences · 2026Article
- Stem Cells and Cell-Free Therapies for Olfactory Epithelium Regeneration: Insights from Experimental Models.International journal of molecular sciences · 2025Review
- New Neurons in the Postnatal Olfactory System: Functions in the Healthy and Regenerating Brain.Brain sciences · 2025Review
- Structural Rearrangement of the Olfactory Epithelium in Male Baikal Yellowfin Sculpins Across the Reproductive Period.Biology · 2025Article
- Neuroimmune interactions in the olfactory epithelium: maintaining a sensory organ at an immune barrier interface.Trends in immunology · 2024Review
- Overview of chromatin regulatory processes during surface ectodermal development and homeostasis.Developmental biology · 2024Review
- Receptors Involved in COVID-19-Related Anosmia: An Update on the Pathophysiology and the Mechanistic Aspects.International journal of molecular sciences · 2024Review
- Dendrite morphogenesis in Caenorhabditis elegans.Genetics · 2024Review
- Type 2 and Non-type 2 Inflammation in the Upper Airways: Cellular and Molecular Alterations in Olfactory Neuroepithelium Cell Populations.Current allergy and asthma reports · 2024Review
- Mechanisms of COVID-19-associated olfactory dysfunction.Neuropathology and applied neurobiology · 2024Review
- A Comprehensive Review of COVID-19-Related Olfactory Deficiency: Unraveling Associations with Neurocognitive Disorders and Magnetic Resonance Imaging Findings.Diagnostics (Basel, Switzerland) · 2024Review
- Reduced olfactory performance is associated with changed microbial diversity, oralization, and accumulation of dead biomaterial in the nasal olfactory area.Microbiology spectrum · 2024Article
- Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019.Journal of translational medicine · 2023Review
- SARS-CoV-2 and Brain Health: New Challenges in the Era of the Pandemic.Microorganisms · 2023Review
- Axonal Regrowth of Olfactory Sensory Neurons In Vitro.International journal of molecular sciences · 2023Article
- The Olfactory Bulb in Companion Animals-Anatomy, Physiology, and Clinical Importance.Brain sciences · 2023Review
- Disrupted chromatin architecture in olfactory sensory neurons: looking for the link from COVID-19 infection to anosmia.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pseudostratified olfactory epithelium (OE) may histologically appear relatively simple, but the cytological relations among its cell types, especially those between olfactory receptor neurons (ORNs) and olfactory sustentacular cells (OSCs), prove more complex and variable than previously believed. Adding to the complexity is the short lifespan, persistent neurogenesis, and continuous rewiring of the ORNs. Contrary to the common belief that ORN dendrites are mostly positioned between OSCs, recent findings indicate a sustentacular cell enwrapped configuration for a majority of mature ORN dendrites at the superficial layer of the OE. After vertically sprouting out from the borderlines between OSCs, most of the immature ORN dendrites undergo a process of sideways migration and terminal maturation to become completely invaginated into and enwrapped by OSCs. Trailing the course of the dendritic sideways migration is the mesodendrite (mesentery of the enwrapped dendrite) made of closely apposed, cell junction connected plasma membrane layers of neighboring folds of the host sustentacular cell. Only a minority of the mature ORN dendrites at the OE apical surface are found at the borderlines between OSCs (unwrapped). Below I give a brief update on the cytoarchitectonic relations between the ORNs and OSCs of the OE. Emphasis is placed on the enwrapment of ORN dendrites by OSCs, on the sideways migration of immature ORN dendrites after emerging from the OE surface, and on the terminal maturation of the ORNs. Functional implications of ORN dendrite enwrapment and a comparison with myelination or Remak's bundling of axons or axodendrites in the central and peripheral nervous system are also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.