Evidence map›Paper›PMID 32365867›Full record

ArticleCancers2020

Usefulness of Two Independent DNA and RNA Tissue-Based Multiplex Assays for the Routine Care of Advanced NSCLC Patients.

Elba Marin, Cristina Teixido, Elena Carmona-Rocha, Roxana Reyes, Ainara Arcocha, Nuria Viñolas, MªCarmen Rodríguez-Mues, Carlos Cabrera, Marcelo Sánchez, Ivan Vollmer and 11 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Elba MarinDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
Cristina TeixidoTranslational Genomics and Targeted Therapeutics in Solid Tumors, Institut d'Investigacions Biomèdiques August Pi I Sunyer, 08036 Barcelona, Spain.ORCID 0000-0002-7226-6567
Elena Carmona-RochaDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
Roxana ReyesDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
Ainara ArcochaDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
Nuria ViñolasDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
MªCarmen Rodríguez-MuesDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
Carlos CabreraDivision of Medical Oncology, Instituto Oncologico Dr. Rosell, Teknon Hospital, 08028 Barcelona, Spain.
Marcelo SánchezUnitat Funcional de Tumors Toràcics, Hospital Clínic, 08036 Barcelona, Spain.
Ivan VollmerUnitat Funcional de Tumors Toràcics, Hospital Clínic, 08036 Barcelona, Spain.
Sergi CastilloDivision of Medical Oncology, Hospital General de Granollers, 08402 Barcelona, Spain.
Silvia MuñozDivision of Medical Oncology, Hospital General de Granollers, 08402 Barcelona, Spain.
Ivana G SullivanDivision of Medical Oncology, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.ORCID 0000-0002-0434-3436
Adela RodriguezDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
Mireia GarciaDivision of Pathology, Hospital Clínic, 08036 Barcelona, Spain.
Silvia AlosDivision of Pathology, Hospital Clínic, 08036 Barcelona, Spain.
Pedro JaresDivision of Pathology, Hospital Clínic, 08036 Barcelona, Spain.
Antonio MartinezDivision of Pathology, Hospital Clínic, 08036 Barcelona, Spain.ORCID 0000-0003-0790-9017
Aleix PratDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.ORCID 0000-0003-2377-540X
Miguel Ángel Molina-VilaLaboratory of Oncology, Pangaea Oncology, Quirón Dexeus University Hospital, 08028 Barcelona, Spain.ORCID 0000-0001-8866-9881
Noemi ReguartDivision of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
Hospital Clínic de Barcelona · ESHospital General de Granollers · ESHospital de Sant Pau · ESHospital Universitario Dexeus · ESInstituto Oncológico Dr. Rosell · ES

Funding

Acción Estratégica en Salud; Instituto de Salud Carlos III FIS16/00890, PI N.Reguart.Novartis CINC280AES01TPfizer WI230526
6 · The paper itself

Abstract

Personalized medicine is nowadays a paradigm in lung cancer management, offering important benefits to patients. This study aimed to test the feasibility and utility of embedding two multiplexed genomic platforms as the routine workup of advanced non-squamous non-small cell lung cancer (NSCLC) patients. Two parallel multiplexed approaches were performed based on DNA sequencing and direct digital detection of RNA with nCounter

Indexed as

advanced non-small cell lung cancermolecular diagnosticsmutationsoncogenic driverstargeted therapies

Identifiers

PMID32365867
PMCPMC7281583
OpenAlexW3023416658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.