Evidence map›Paper›PMID 32365848›Full record

ArticleNutrients2020

Impact of Nutrient Intake on Hydration Biomarkers Following Exercise and Rehydration Using a Clustering-Based Approach.

Colleen X Muñoz, Evan C Johnson, Laura J Kunces, Amy L McKenzie, Michael Wininger, Cory L Butts, Aaron Caldwell, Adam Seal, Brendon P McDermott, Jakob Vingren and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Colleen X MuñozUniversity of Hartford, West Hartford, CT 06117, USA.
Evan C JohnsonUniversity of Wyoming, Laramie, WY, USA.
Laura J KuncesOnegevity Health, New York, NY, USA.
Amy L McKenzieVirta Health, San Francisco, CA, USA.
Michael WiningerUniversity of Hartford, West Hartford, CT 06117, USA.
Cory L ButtsUniversity of Arkansas, Fayetteville, AR 72701, USA.
Aaron CaldwellUniversity of Arkansas, Fayetteville, AR 72701, USA.
Adam SealUniversity of Arkansas, Fayetteville, AR 72701, USA.
Brendon P McDermottUniversity of Arkansas, Fayetteville, AR 72701, USA.
Jakob VingrenUniversity of North Texas, Denton, TX 76203, USA.
Abigail T ColburnUniversity of Connecticut, Storrs, CT 06269, USA.
Skylar S WrightUniversity of Connecticut, Storrs, CT 06269, USA.
Virgilio Lopez IiiUniversity of Connecticut, Storrs, CT 06269, USA.
Lawrence E ArmstrongUniversity of Connecticut, Storrs, CT 06269, USA.
Elaine C LeeUniversity of Connecticut, Storrs, CT 06269, USA.
University of Connecticut · USWeber State University · USUniversity of Hartford · USUniversity of North Texas · USUniversity of Wyoming · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the impact of nutrient intake on hydration biomarkers in cyclists before and after a 161 km ride, including one hour after a 650 mL water bolus consumed post-ride. To control for multicollinearity, we chose a clustering-based, machine learning statistical approach. Five hydration biomarkers (urine color, urine specific gravity, plasma osmolality, plasma copeptin, and body mass change) were configured as raw- and percent change. Linear regressions were used to test for associations between hydration markers and eight predictor terms derived from 19 nutrients merged into a reduced-dimensionality dataset through serial k-means clustering. Most predictor groups showed significant association with at least one hydration biomarker: 1) Glycemic Load + Carbohydrates + Sodium, 2) Protein + Fat + Zinc, 3) Magnesium + Calcium, 4) Pinitol, 5) Caffeine, 6) Fiber + Betaine, and 7) Water; potassium + three polyols, and mannitol + sorbitol showed no significant associations with any hydration biomarker. All five hydration biomarkers were associated with at least one nutrient predictor in at least one configuration. We conclude that in a real-life scenario, some nutrients may serve as mediators of body water, and urine-specific hydration biomarkers may be more responsive to nutrient intake than measures derived from plasma or body mass.

Indexed as

Fluid TherapyAdultAgedBicyclingBiomarkersCluster AnalysisDrinkingEatingFemaleGlycopeptidesHumansLinear ModelsMachine LearningMaleMiddle AgedNutritional Physiological PhenomenaBiomarkerscopeptinsGlycopeptidesclusteringcollinearitycopeptinexercisehydrationnutritionsport nutrition

Identifiers

PMID32365848
PMCPMC7282025
OpenAlexW3022714776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.