Evidence map›Paper›PMID 32365686›Full record

ReviewDiagnostics (Basel, Switzerland)2020

Role of Peroral Cholangioscopy in the Diagnosis of Primary Sclerosing Cholangitis.

Toshio Fujisawa, Mako Ushio, Sho Takahashi, Wataru Yamagata, Yusuke Takasaki, Akinori Suzuki, Yoshihiro Okawa, Kazushige Ochiai, Ko Tomishima, Shigeto Ishii and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Contribution of Endoscopy in the Diagnosis and Treatment of Patients With Primary Sclerosing Cholangitis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Article
  3. Endoscopic management of primary sclerosing cholangitis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Review
  4. Article
  5. Peroral cholangioscopy: Update on the state-of-the-art.World journal of gastrointestinal endoscopy · 2022
    Article
  6. Choledochoscopy: An update.World journal of gastrointestinal endoscopy · 2021
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Toshio FujisawaDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Mako UshioDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Sho TakahashiDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Wataru YamagataDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Yusuke TakasakiDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Akinori SuzukiDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Yoshihiro OkawaDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Kazushige OchiaiDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Ko TomishimaDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Shigeto IshiiDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Hiroaki SaitoDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Hiroyuki IsayamaDepartment of Gastroenterology, Juntendo University Graduate School of Medicine, Tokyo 113-8421 , Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary sclerosing cholangitis (PSC) is characterized by idiopathic biliary stricture followed by progressive cholestasis and fibrosis. When diagnosing PSC, its differentiation from other types of sclerosing cholangitis and cholangiocarcinoma is necessary. The cholangioscopic findings of PSC have not been investigated sufficiently. PSC and IgG4-related sclerosing cholangitis are difficult to distinguish by peroral cholangioscopy (POCS), but POCS is useful for excluding cholangiocarcinoma. POCS findings vary according to the condition and stage of disease. In the active phase, findings such as mucosal erythema, ulceration, fibrinous white exudate, and an irregular surface are observed and may reflect strong inflammation in the biliary epithelium. On the other hand, findings such as scarring, pseudodiverticula, and bile duct stenosis appear in the chronic phase and may reflect fibrosis and stenosis resulting from repeated inflammation. Observation of inside the bile duct by POCS might confirm the current PSC activity. Because POCS offers not only information regarding the diagnosis of PSC and PSC-associated cholangiocarcinoma but also the current statuses of biliary inflammation and stenosis, POCS could significantly contribute to the diagnosis and treatment of PSC once the characteristic findings of PSC are confirmed by future studies.

Indexed as

active phasecholangiocarcinomacholangioscopychronic phaseIgG4-related sclerosing cholangitisprimary sclerosing cholangitispseudodiverticulascarring

Identifiers

PMID32365686
PMCPMC7277921
OpenAlexW3023828473

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.