Evidence map›Paper›PMID 32365581›Full record

ArticleCancers2020

The Prognostic and Predictive Value of SOX2

Tim J Miller, Melanie J McCoy, Tracey F Lee-Pullen, Chidozie C Anyaegbu, Christine Hemmings, Max K Bulsara, Cameron F Platell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Cancer Stem Cells from Definition to Detection and Targeted Drugs.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Tim J MillerMedical School, University of Western Australia, M507, 35 Stirling Highway, Crawley, WA 6009, Australia.ORCID 0000-0002-0473-1869
Melanie J McCoyMedical School, University of Western Australia, M507, 35 Stirling Highway, Crawley, WA 6009, Australia.ORCID 0000-0002-7402-2718
Tracey F Lee-PullenMedical School, University of Western Australia, M507, 35 Stirling Highway, Crawley, WA 6009, Australia.ORCID 0000-0003-3713-9674
Chidozie C AnyaegbuMedical School, University of Western Australia, M507, 35 Stirling Highway, Crawley, WA 6009, Australia.
Christine HemmingsDepartment of Anatomic Pathology, Canterbury Health Laboratories, Christchurch 8013, New Zealand.ORCID 0000-0001-9914-3017
Max K BulsaraInstitute for Health Research, University of Notre Dame, P.O. Box 1225, Fremantle, WA 6959, Australia.
Cameron F PlatellMedical School, University of Western Australia, M507, 35 Stirling Highway, Crawley, WA 6009, Australia.
St John of God Subiaco Hospital · AUCanterbury Health Laboratories · NZThe University of Notre Dame Australia · AUThe University of Western Australia · AU

Funding

St. John of God Foundation Not ApplicableTonkinson Colorectal Cancer Research Fund Not Applicable
6 · The paper itself

Abstract

SOX2 (sex-determining region-Y homeobox-2) is a transcription factor essential for the maintenance of pluripotency and is also associated with stem-cell-like properties in preclinical cancer models. Our previous study on a cohort of stage III colon cancer patients demonstrated high SOX2

Indexed as

5-fluorouracilcancer stem cellchemotherapycolorectal canceroxaliplatinprognosisSOX2

Identifiers

PMID32365581
PMCPMC7280991
OpenAlexW3021287909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.